Loss of LPR8 Reduces GPX4 Levels, Resulting in Ferroptosis Sensitivity
- PMID: 35713354
- DOI: 10.1158/2159-8290.CD-RW2022-109
Loss of LPR8 Reduces GPX4 Levels, Resulting in Ferroptosis Sensitivity
Abstract
LPR8 was identified as a factor contributing to ferroptosis resistance in multiple tumor types.
©2022 American Association for Cancer Research.
Comment on
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Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability.Nat Chem Biol. 2022 Jul;18(7):751-761. doi: 10.1038/s41589-022-01033-3. Epub 2022 May 30. Nat Chem Biol. 2022. PMID: 35637349 Free PMC article.
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