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. 2022 Jun 17;19(6):e1004027.
doi: 10.1371/journal.pmed.1004027. eCollection 2022 Jun.

Cancer systems epidemiology: Overcoming misconceptions and integrating systems approaches into cancer research

Patricia L Mabry  1 , Nicolaas P Pronk  1   2 , Christopher I Amos  3   4 , John S Witte  5 , Patrick T Wedlock  6   7 , Sarah M Bartsch  6   7 , Bruce Y Lee  6   7
Affiliations

Cancer systems epidemiology: Overcoming misconceptions and integrating systems approaches into cancer research

Patricia L Mabry et al. PLoS Med. .

Abstract

Patricia Mabry and coauthors discuss application of systems approaches in cancer research.

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Conflict of interest statement

I have read the journal’s policy and the authors of this manuscript have the following competing interests: PLM sits on the Board of Directors as Board Chair of Computer Simulation and Advance Research Technologies (since 2019), a non-profit with charity status in Australia and is an Advisory Board member to the Systems-science Informed Public Health Economic Research for Non-communicable Disease Prevention Consortium (SIPHER, since 2019), a research project based in the United Kingdom and funded by the UK Prevention Research Partnership. PLM is PI on a project entitled, SCISIPBIO: Constructing Heterogeneous Scholarly Graphs to Examine Social Capital During Mentored K Awardees Transition to Research Independence: Explicating a Matthew Mechanism, funded by the U.S. National Science Foundation. JSW is a co-founder of Avail Bio and is paid expert work from Pfizer and Sanofi.

Figures

Fig 1
Fig 1. Systems approaches should be iterative.
Fig 2
Fig 2. Systems modeling and approaches can and do occur at different points along the research path from idea inception to policy implementation.
See this image and copyright information in PMC

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