What Intracardiac Tracings Have Taught Us About Left Bundle Branch Block

Abstract

Current electrocardiogram (ECG) criteria for left bundle branch block (LBBB) are largely based on early work in animal models or on mathematical models of cardiac activation. The resulting criteria have modest specificity, and up to one-third of patients who meet current ECG criteria for LBBB may have intact conduction through their His-Purkinje systems. Intracardiac tracings offer the ability to accurately discriminate between LBBB and other causes of delayed activation, which may facilitate the development of more accurate ECG criteria. Assessing these distinctions are particularly salient to applications for conduction system pacing.

Keywords: Conduction system pacing; His bundle pacing; Left bundle branch area pacing; Left ventricular septal pacing.