Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Jun 3:9:905504.
doi: 10.3389/fcvm.2022.905504. eCollection 2022.

Hypertension in Women

Affiliations
Review

Hypertension in Women

Tatjana Tasić et al. Front Cardiovasc Med. .

Abstract

Hypertension is one of the main causes of morbidity and mortality in the human population. Nevertheless, the intricate network of pathophysiological mechanisms that lead to the development of hypertension in women still awaits to be fully understood. From young age to maturity and senescence, the female body transits through different stages, each of them characterized with specific physiological features and disposition to particular pathological conditions, and that is exactly what makes the understanding of the genesis and adequate treatment of hypertension in women so challenging. Clinical and experimental findings emphasize the role of sex hormones, autonomic nervous system, renin-angiotensin-aldosterone system and arterial stiffness in the development of chronically elevated blood pressure in females. The purpose of this review is to briefly summarize the knowledge of the mechanisms and treatment of hypertension in women.

Keywords: antihypertensive treatment; postmenopausal hypertension; pregnancy induced hypertension; sex differences; sex hormones.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Similar articles

Cited by

  • Hypertension: A Continuing Public Healthcare Issue.
    Goorani S, Zangene S, Imig JD. Goorani S, et al. Int J Mol Sci. 2024 Dec 26;26(1):123. doi: 10.3390/ijms26010123. Int J Mol Sci. 2024. PMID: 39795981 Free PMC article. Review.
  • Biosocial predictors and blood pressure goal attainment among postmenopausal women with hypertension.
    Kandasamy G, Subramani T, Sam G, Almanasef M, Almeleebia T, Shorog E, Alshahrani AM, Hmlan A, Al Suhaym AY, Prabahar K, Veeramani VP, Amirthalingam P. Kandasamy G, et al. Front Cardiovasc Med. 2024 Feb 16;11:1268791. doi: 10.3389/fcvm.2024.1268791. eCollection 2024. Front Cardiovasc Med. 2024. PMID: 38433758 Free PMC article.
  • Editorial: Women in hypertension.
    Dorobantu M, Sorriento D. Dorobantu M, et al. Front Cardiovasc Med. 2023 Mar 24;10:1156589. doi: 10.3389/fcvm.2023.1156589. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37034330 Free PMC article. No abstract available.
  • Hyperuricemia and Endothelial Function: Is It a Simple Association or Do Gender Differences Play a Role in This Binomial?
    Ciarambino T, Crispino P, Giordano M. Ciarambino T, et al. Biomedicines. 2022 Nov 29;10(12):3067. doi: 10.3390/biomedicines10123067. Biomedicines. 2022. PMID: 36551823 Free PMC article. Review.
  • Brazilian Guideline on Menopausal Cardiovascular Health - 2024.
    Oliveira GMM, Almeida MCC, Arcelus CMA, Neto Espíndola L, Rivera MAM, Silva-Filho ALD, Marques-Santos C, Fernandes CE, Albuquerque CJDM, Freire CMV, Izar MCO, Costa MENC, Castro ML, Lemke VMG, Lucena AJG, Brandão AA, Macedo AVS, Polanczyk CA, Lantieri CJB, Nahas EP, Alexandre ERG, Campana EMG, Bragança ÉOV, Colombo FMC, Barbosa ICQ, Rivera IR, Kulak J, Moura LAZ, Pompei LM, Baccaro LFC, Barbosa MM, Rodrigues MAH, Albernaz MA, Decoud MSP, Paiva MSMO, Sanchez-Zambrano MB, Campos MDSB, Acevedo M, Ramirez MS, Souza OF, Medeiros OO, Carvalho RCM, Machado RB, Silva SCTFD, Rodrigues TCV, Avila WS, Costa-Paiva LHSD, Wender MCO. Oliveira GMM, et al. Arq Bras Cardiol. 2024 Aug 16;121(7):e20240478. doi: 10.36660/abc.20240478. Arq Bras Cardiol. 2024. PMID: 39166619 Free PMC article. English, Portuguese. No abstract available.

References

    1. Ong KL, Tso AWK, Lam KSL, Cheung BMY. Gender difference in blood pressure control and cardiovascular risk factors in Americans with diagnosed hypertension. Hypertension. (2008) 51:1142–8. 10.1161/HYPERTENSIONAHA.107.105205 - DOI - PubMed
    1. Whelton PK, Carey RM, Aronow WS, Casey DEJr, Collins KJ, Dennison Himmelfarb C, et al. . 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the american college of cardiology/American heart association task force on clinical practice guidelines. J Am Coll Cardiol. (2018) 71:e127–248. 10.1016/j.jacc.2017.11.006 - DOI - PubMed
    1. Giosia P, Giorgini P, Stamerra CA, Petrarca M, Ferri C, Sahebkar A. Gender differences in epidemiology, pathophysiology, and treatment of hypertension. Curr Atheroscler Rep. (2018) 20:13. 10.1007/s11883-018-0716-z - DOI - PubMed
    1. Rosei EA, Chiarini G, Rizzoni D. How important is blood pressure variability? Eur Heart J. (2020) 22:E1–6. 10.1093/eurheartj/suaa061 - DOI - PMC - PubMed
    1. Tadic M, Cuspidi C, Sljivic A, Pencic B, Mancia G, Bombelli M, et al. . Do reverse dippers have the highest risk of ventricular remodeling? Hypertens Res. (2020) 43:213–9. 10.1038/s41440-019-0351-2 - DOI - PubMed

LinkOut - more resources