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. 2021 Jul 29;13(4):332-336.
doi: 10.1136/flgastro-2021-101886. eCollection 2022.

Guideline review: EASL clinical practice guidelines: drug-induced liver injury (DILI)

Paul N Brennan  1   2 , Peter Cartlidge  3 , Thomas Manship  4 , John F Dillon  3   5
Affiliations

Guideline review: EASL clinical practice guidelines: drug-induced liver injury (DILI)

Paul N Brennan et al. Frontline Gastroenterol. .

Abstract

The European Association for the Study of the Liver has produced extensive guidelines for the investigation and management of drug-induced liver injury. Here, we provide a commentary and overview of some of the principle disease investigations and management that arise from these guideline recommendations.

Keywords: drug induced hepatotoxicity; drug induced liver injury; drug metabolism; drug toxicity.

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Conflict of interest statement

Competing interests: JFD has received research grants and lecture honoraria from MSD, Abbvie and Gilead.

Figures

Figure 1
Figure 1
Suggested approach to presentation of drug-induced liver injury (DILI). ANA, antinuclear antibody; BC, Budd-Chiari syndrome; CMV, cytomegalovirus; EBV, Epstein-Barr virus; HAV, hepatitis A virus; HBV, hepatitis B virus; HCV, hepatitis C virus; HEV, hepatitis E virus; HSV, hepes simplex virus; HCC, hepatocellular carcinoma; LKM, liver microsomal antibody; NRH, nodular regenerative hyperplasia; PBC, primary biliary cholangitis; PSC, primary sclerosing cholangitis; PVT, portal vein thrombosis; SMA, smooth muscle antibody; USS, ultransound scan; VZV, varicella zoster virus.
See this image and copyright information in PMC

References

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