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. 2022 Jul;51(5):2451-2464.
doi: 10.1007/s10508-022-02322-7. Epub 2022 Jun 20.

PrEP in the Context of Other HIV Risk Reduction Strategies Among Men Who Have Sex with Men: Results from the Flash! PrEP in Europe Survey

Marion Di Ciaccio  1   2 , Rosemary M Delabre  3 , Antoine Vilotitch  4   5 , Giulio Maria Corbelli  6 , Virginie Villes  3 , Alejandro Ros Sánchez  3 , Paul Zantkuijl  7 , Holger Sweers  8 , Flor Sanchez  9 , Michael Meulbroek  10 , Gus Cairns  11 , Adeline Bernier  3 , Jade Ghosn  12 , Luìs Miguel Carvalho Rocha  13 , Maria Luisa Cosmaro  14 , Sascha Béla Duken  15 , Monica Dan  16 , Vincent Schlegel  17 , Richard Stranz  3   17 , Kai J Jonas  18 , Bruno Spire  4 , Daniela Rojas Castro  3   4
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PrEP in the Context of Other HIV Risk Reduction Strategies Among Men Who Have Sex with Men: Results from the Flash! PrEP in Europe Survey

Marion Di Ciaccio et al. Arch Sex Behav. 2022 Jul.

Abstract

Combination HIV prevention covers a range of biomedical, behavioral, and socio-structural interventions. Despite the growing availability of pre-exposure prophylaxis (PrEP), it is not always accessible in European Centre for Disease Prevention and Control reporting countries and may not meet the needs of all at-risk populations. Based on the Flash! PrEP in Europe data, multiple correspondence analysis and hierarchical clustering were used to identify patterns in HIV prevention strategies among 9980 men who have sex with men (MSM). PrEP interest was evaluated among four identified clusters: (A) "high condom use, sometimes Treatment as Prevention (TasP)"; (B) "mix of methods, infrequent condom use"; (C) "high condom use, tendency to choose partners based on serological status" and (D) "moderate use of condoms mixed with other prevention strategies". Clusters B and D had higher PrEP interest. These results suggest that MSM use a range of behavioral and biomedical risk reduction strategies that are often combined. On-demand PrEP may meet the needs of MSM who infrequently use condoms and other prevention methods.

Keywords: Community-based research; Europe; HIV prevention; MSM; PrEP; Sexual orientation.

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Conflict of interest statement

ARS is a former employee of Wyeth and Pfizer laboratories, and holds Pfizer stock. J.G. reports personal fees from Merck, grants and personal fees from ViiV Healthcare, grants and personal fees from Gilead Sciences, personal fees from Roche, personal fees from AstraZeneca, personal fees from Janssen, outside the submitted work. The other authors do not declare any conflicts of interest.

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