Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Mar;90(3):233-239.
doi: 10.1007/s12098-022-04252-7. Epub 2022 Jun 21.

Survival and Neurodevelopmental Outcome of Extremely-Low-Birth-Weight Infants at One Year of Age-A Prospective, Descriptive Study

K P K N Venkataramana  1 , Vaanathi Hementha Kumar  2 , Natarajan Chandra Kumar  1 , Shanmuga Sundaram C  1 , Ahalya Dhanalaksmi  1
Affiliations

Survival and Neurodevelopmental Outcome of Extremely-Low-Birth-Weight Infants at One Year of Age-A Prospective, Descriptive Study

K P K N Venkataramana et al. Indian J Pediatr. 2023 Mar.

Abstract

Objectives: To study the survival rates at discharge and neurodevelopmental outcome at 1 y of corrected age (CA) of extremely-low-birth-weight ELBW neonates.

Methods: This prospective, descriptive study was conducted in a tertiary care level III extramural NICU of a teaching hospital. Forty-nine extremely-low-birth-weight (ELBW) neonates were enrolled in the study from July 2017 to June 2018. Baseline demographic data, morbidities during NICU stay, and survival at discharge for the enrolled neonates were recorded. The enrolled infants were followed up to 1 y of CA at three-monthly intervals. During the follow-up, anthropometry, developmental screening by Denver Developmental Screening Test (DDST), and tone assessment by Amiel-Tison scale were done. Developmental Assessment Scale for Indian Infants (DASII) was administered at CA of 12 mo.

Results: Thirty-seven (75.5%) neonates survived to discharge. Survival rate of neonates with birth weight > 750 g and with gestational age ≥ 26 wk was 90.2% and 85.7%, respectively. Amongst those < 750 g or < 26 wk (n = 8), none survived. Abnormal developmental quotient (DQ < 70%) was seen in 6 infants out of 33 infants (18.1%) followed at 1 y of CA.

Conclusion: Overall, 3/4th of ELBW infants survived to discharge and 80% of those who were followed up at 1 y of CA had normal neurodevelopmental outcome. However, survival rates of neonates born at < 26 wk and/or with birth weight < 750 g were less and needs to be improved.

Keywords: ELBW; Follow-up; Neurodevelopmental outcome; Survival.

PubMed Disclaimer

Comment in

References

    1. Ministry of Health and Family Welfare, GOI. India Newborn Action Plan (INAP). Available at: https://www.newbornwhocc.org/INAP_Final.pdf . Accessed on Sept 2014.
    1. Higgins RD, Jobe AH, Koso-Thomas M, et al. Bronchopulmonary dysplasia: executive summary of a workshop. J Pediatr. 2018;197:300–8. - DOI - PubMed - PMC
    1. Volpe JJ. Volpe’s Neurology of the Newborn. 6th ed. Philadelphia, PA: Elsevier; 2018. p. 1224.
    1. Gregory KE, DeForge CE, Natale KM, Phillips M, Van Marter LJ. Necrotizing enterocolitis in the premature infant: neonatal nursing assessment, disease pathogenesis, and clinical presentation. Adv Neonatal Care. 2011;11:155–64. - DOI - PubMed - PMC
    1. Agarwal K, Jalali S. Classification of retinopathy of prematurity: from then till now. Community Eye Health. 2018;31:S4-7. - PubMed - PMC

LinkOut - more resources