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Review
. 2022 Jul;10(6):594-600.
doi: 10.1002/ueg2.12265. Epub 2022 Jun 21.

Irritable bowel syndrome with food-related symptoms: Future directions in the clinical management

Chloé Melchior  1   2   3 , Joost Algera  1 , Esther Colomier  1   4 , Hans Törnblom  1 , Magnus Simrén  1   5
Affiliations
Review

Irritable bowel syndrome with food-related symptoms: Future directions in the clinical management

Chloé Melchior et al. United European Gastroenterol J. 2022 Jul.

Abstract

The majority of patients with irritable bowel syndrome (IBS) experiences food-related symptoms, which are associated with high symptom burden, reduced quality of life, increased healthcare consumption and reduced intake of certain nutrients. In this review we aimed to describe a clinically useful approach for physicians, by presenting the latest progress in knowledge and its translation to management in IBS patients with food-related symptoms, as well as the underlying mechanisms involved. The research tools currently available that can be used in the future for a better characterization of this subgroup of patients are also discussed. Working towards this approach could lead to a more individualised work-up and management of IBS patients with food-related symptoms.

Keywords: IBS; food-related symptoms; future directions; high symptom burden; individualized management of IBS; irritable bowel syndrome; quality of life; research tools.

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Conflict of interest statement

Chloé Melchior has served as a consultant/advisory board member for Kyowa Kirin, Norgine, Biocodex, Mayoly Spindler, Tillots, and Ipsen. Magnus Simrén has received unrestricted research grants from Danone Nutricia Research, and Glycom; served as a consultant/advisory board member for Danone Nutricia Research, Ironwood, Menarini, Biocodex, GeneticAnalysis AS, Glycom, Arena, and Adnovate and been on the Speakers' bureau for Tillotts, Menarini, Kyowa Kirin, Takeda, Shire, Biocodex, Alimentary Health, Alfasigma, and Falk Foundation. Joost Algera, Esther Colomier and Hans Törnblom have no conflicts of interest to declare.

Figures

FIGURE 1
FIGURE 1
Clinical approach in irritable bowel syndrome (IBS) patients with food‐related gastrointestinal (GI) symptoms
FIGURE 2
FIGURE 2
Future tools in the clinical approach of irritable bowel syndrome (IBS) patients with food‐related symptoms
See this image and copyright information in PMC

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