Odontogenic fibromyxoma: A case report in myasthenia gravis patient and review of the literature

Abstract

Introduction and importance: Odontogenic fibromyxoma is generally slow-growing, benign, asymptomatic, present with painless swelling in the jaw. Pain is mostly seen in the case of infection, adjacent anatomical structures or neural involvement. When the English-language literature is searched, only 62 cases are found about odontogenic fibromxoma which means it is really rare pathology.

Case presentation: We describe a case of odontogenic fibromyxoma in a 29-year-old female with Myasthenia Gravis (MG) who referred to oral and maxillofacial surgeon with increased swelling in the anterior region of the mandible.

Clinical discussion: Clinically, there was swelling in the mouth that caused bone expansion. On the radiological examination, a well-circumscribed, radiolucent area causing displacement of the tooth roots was observed. After clinical and radiological examinations, the operation was done under local anesthesia. The excised lesion was sent for histopathological investigation and the patient was followed up clinically and radiologically for 3 years.

Conclusion: The clinical and radiological properties, differential diagnosis, treatment options and prognosis of odontogenic fibromyxomas are also discussed after the case presentation along with literature review.

Keywords: Fibromyxoma; Myasthenia gravis; Myxofibroma; Odontogenic fibromyxoma; Odontogenic myxofibroma.

Fig. 1

Front view of the mouth.

Fig. 2

Lateral view of the mouth.

Fig. 3

First panaromic radiograph of the patient.

Fig. 4

Intraoral view during surgery after periosteal elevation.

Fig. 5

Appearance after tooth extraction and removal of the lesion.

Fig. 6

Appearance of the removed lesion.

Fig. 7

Histopathological image at ×10 magnification.

Fig. 8

Histopathological image at ×20 magnification.

Fig. 9

Panaromic radiograph taken 6 months after the operation.

Fig. 10

Panoramic radiograph taken 1 year after the operation.

Fig. 11

Panoramic radiograph taken 3 years after the operation.