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Review
. 2022 Nov;24(11):2055-2063.
doi: 10.1007/s12094-022-02866-z. Epub 2022 Jun 21.

MiRNAs in renal cell carcinoma

Jesús Miranda-Poma  1 , Lucía Trilla-Fuertes  2 , Elena López-Camacho  2 , Andrea Zapater-Moros  2 , Rocío López-Vacas  2 , María Isabel Lumbreras-Herrera  2 , Ana Pertejo-Fernandez  3 , Juan Ángel Fresno-Vara  2   4   5 , Enrique Espinosa-Arranz  3 , Angelo Gámez-Pozo  2   4 , Álvaro Pinto-Marín  3
Affiliations
Review

MiRNAs in renal cell carcinoma

Jesús Miranda-Poma et al. Clin Transl Oncol. 2022 Nov.

Abstract

MicroRNAs (miRNAs) are small RNA sequences that act as post-transcriptional regulatory genes to control many cellular processes through pairing bases with a complementary messenger RNA (mRNA). A single miRNA molecule can regulate more than 200 different transcripts and the same mRNA can be regulated by multiple miRNAs. In this review, we highlight the importance of miRNAs and collect the existing evidence on their relationship with kidney cancer.

Keywords: Kidney cancer; Renal cancer; miRNA; microRNA.

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