Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Jun 13;10(6):e5978.
doi: 10.1002/ccr3.5978. eCollection 2022 Jun.

Drug-induced vasculitis: Thiazide or the COVID-19 vaccine, which one is guilty? A case report and literature review

Manoochehr Hekmat  1 , Sepideh Jafari Naeini  2 , Zahra Abbasi  3 , Sahar Dadkhahfar  4
Affiliations
Case Reports

Drug-induced vasculitis: Thiazide or the COVID-19 vaccine, which one is guilty? A case report and literature review

Manoochehr Hekmat et al. Clin Case Rep. .

Abstract

A middle-aged woman with a history of COVID-19 vaccine administration and valve replacement surgery was admitted with bilateral palpable purpuric lesions in the lower extremities and headache. Based on the initial diagnosis of vasculitis, corticosteroid therapy was initiated, which led to the resolution of skin lesions.

Keywords: COVID‐19 vaccines; thiazides; vasculitis; warfarin.

PubMed Disclaimer

Conflict of interest statement

None declared.

Figures

FIGURE 1
FIGURE 1
Palpable purpuric lesions in both lower extremities with hemorrhagic changes
FIGURE 2
FIGURE 2
(A) Spiral brain computed tomography (CT) showed evidence of acute and subacute foci of For Review Only subdural hematoma adjacent to the left temporal lobe. (B) The hemorrhagic lesion disappeared after 1 month
FIGURE 3
FIGURE 3
Cutaneous lesions disappeared gradually after the initiation of corticosteroid
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Morita T, Trés GFS, Criado RFJ, Sotto MN, Criado PR. Update on vasculitis: an overview and dermatological clues for clinical and histopathological diagnosis ‐ part I. An Bras Dermatol. 2020;95(3):355‐371. - PMC - PubMed
    1. Radić M, Martinović Kaliterna D, Radić J. Drug‐induced vasculitis: a clinical and pathological review. Neth J Med. 2012;70(1):12‐17. - PubMed
    1. Tawanwongsri W, Chayavichitsilp P. Methimazole‐induced Leukocytoclastic Vasculitis: a case report. Case Rep Dermatol. 2019;11(3):303‐309. - PMC - PubMed
    1. Hsu CY, Chen WS, Sung SH. Warfarin‐induced leukocytoclastic vasculitis: a case report and review of literature. Intern Med. 2012;51(6):601‐606. - PubMed
    1. Misra D, Patro P, Sharma A. Drug‐induced vasculitis. Indian J Rheumatol. 2019;14(5):3‐9.

Publication types

LinkOut - more resources