An official website of the United States government
The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before
sharing sensitive information, make sure you’re on a federal
government site.
The site is secure.
The https:// ensures that you are connecting to the
official website and that any information you provide is encrypted
and transmitted securely.
1 State Key Laboratory of Bioorganic and Natural Products Chemistry, Research Center of Chemical Kinomics, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
2 School of Medicine, Institute of Cardiovascular Diseases, Xiamen Cardiovascular Hospital Xiamen University, Xiamen University, Xiamen, China.
3 Hatherly Laboratories, College of Medicine and Health, Institute of Biomedical and Clinical Sciences, University of Exeter Medical School, Streatham Campus, Exeter, United Kingdom.
4 State Key Laboratory of Virology, Frontier Science Center for Immunology and Metabolism, Department of Anesthesiology, College of Life Sciences, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
5 The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, China.
1 State Key Laboratory of Bioorganic and Natural Products Chemistry, Research Center of Chemical Kinomics, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
2 School of Medicine, Institute of Cardiovascular Diseases, Xiamen Cardiovascular Hospital Xiamen University, Xiamen University, Xiamen, China.
3 Hatherly Laboratories, College of Medicine and Health, Institute of Biomedical and Clinical Sciences, University of Exeter Medical School, Streatham Campus, Exeter, United Kingdom.
4 State Key Laboratory of Virology, Frontier Science Center for Immunology and Metabolism, Department of Anesthesiology, College of Life Sciences, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
5 The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, China.
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Comment on
Editorial on the Research Topic Role of Ion Channels in Pain
References
Abdulqawi R., Dockry R., Holt K., Layton G., Mccarthy B. G., Ford A. P., et al. (2015). P2X3 Receptor Antagonist (AF-219) in Refractory Chronic Cough: a Randomised, Double-Blind, Placebo-Controlled Phase 2 Study. Lancet 385, 1198–1205. 10.1016/S0140-6736(14)61255-1
-
DOI
-
PubMed
Akopian A. N., Sivilotti L., Wood J. N. (1996). A Tetrodotoxin-Resistant Voltage-Gated Sodium Channel Expressed by Sensory Neurons. Nature 379, 257–262. 10.1038/379257a0
-
DOI
-
PubMed
Caterina M. J., Julius D. (2001). The Vanilloid Receptor: a Molecular Gateway to the Pain Pathway. Annu. Rev. Neurosci. 24, 487–517. 10.1146/annurev.neuro.24.1.487
-
DOI
-
PubMed
Caterina M. J., Schumacher M. A., Tominaga M., Rosen T. A., Levine J. D., Julius D. (1997). The Capsaicin Receptor: a Heat-Activated Ion Channel in the Pain Pathway. Nature 389, 816–824. 10.1038/39807
-
DOI
-
PubMed
Coste B., Mathur J., Schmidt M., Earley T. J., Ranade S., Petrus M. J., et al. (2010). Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels. Science 330, 55–60. 10.1126/science.1193270
-
DOI
-
PMC
-
PubMed