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Review
. 2022 Oct;46(10):e14282.
doi: 10.1111/jfbc.14282. Epub 2022 Jun 23.

Pharmacological effects of D-Pinitol - A comprehensive review

Anandakumar Pandi  1 , Kamaraj Sattu  2 , Vanitha M Kalappan  3 , Vanita Lal  1 , Seshadri R Varikasuvu  1 , Anirban Ganguly  1 , Jitender Prasad  1
Affiliations
Review

Pharmacological effects of D-Pinitol - A comprehensive review

Anandakumar Pandi et al. J Food Biochem. 2022 Oct.

Abstract

In recent years, the application of phytochemicals to prevent or treat diseases has received greater attention. These phytochemicals have little or no toxicity against healthy tissues and are thus considered as ideal compounds. An impressive number of modern drugs are obtained from natural sources based on their traditional value. D-Pinitol is a natural compound that is derived from soy and soy products. It is a potentially active molecule that belongs to the class of inositols. D-pinitol has been pharmacologically evaluated for its potent antioxidant, anti-diabetic, anti-inflammatory, anti-cancer, hepatoprotective, cardioprotective, renoprotective, neuroprotective, immunosuppressive, and anti-osteoporotic efficacies. This review is an attempt to validate the plausible pharmacological effects of D-pinitol using various in vivo and in vitro studies. PRACTICAL IMPLICATIONS: The consumption of plant-based products has been significantly increased all over the world. The active phytochemicals that are found in plants are stated to have numerous health promoting functions for the treatment of diabetes, cancer, inflammation, cardiac diseases, liver dysfunction, and many other. D-Pinitol is abundantly present in soybeans that possess notable therapeutic activities. Understanding the effects of D-Pinitol would potentially help in applying this compound in clinical research for the treatment of different disorders.

Keywords: D-pinitol; anti-cancer; anti-diabetic; anti-inflammatory; antioxidant; cardioprotective; hepatoprotective; neuroprotective; renoprotective.

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References

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