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. 2022 Oct;94(10):4850-4859.
doi: 10.1002/jmv.27955. Epub 2022 Jul 9.

Epidemiological features and sociodemographic factors associated with mumps in mainland China from 2004 to 2018

Xiaofang Fu  1 , Minjie Ge  1 , Wucheng Xu  1 , Min Yu  1 , Jiangang Ju  1 , Yonghong Zhong  1 , Huaqiong Huang  2
Affiliations

Epidemiological features and sociodemographic factors associated with mumps in mainland China from 2004 to 2018

Xiaofang Fu et al. J Med Virol. 2022 Oct.

Abstract

Mumps is an acute infectious disease that spreads widely around the world. The aim of this study was to investigate the epidemiological features and sociodemographic factors associated with mumps in mainland China from 2004 to 2018. Incidence data for mumps during the period 2004-2018 were collected from the Public Health Sciences Data Center of China. Joinpoint regression analysis was performed to explore the trends of mumps. Space-time clustering analysis was conducted to spatial and temporal aggregation areas of mumps. A generalized linear model was used to explore sociodemographic factors associated with the incidence of mumps. The average annual incidence of mumps was 21.44/100 000 in mainland China. It was increased dramatically during 2004-2012 (annual percentage change​ [​​​​​​APC] = 7.51, 95% confidence interval [CI]: 2.28-13.00). After 2012, it remained stable, however, significantly increased in intermediately developed regions from 2015 to 2018 (APC = 25.84, 95% CI: 3.59-52.86). The first-level spatial and temporal aggregation areas were distributed in Xinjiang, Gansu, Qinghai, Ningxia and Shaanxi, Tibet, Sichuan, Yunnan, Chongqing, Guizhou, and Guangxi, with gathering times from January 1, 2006 to December 31, 2012 (relative risk [RR] = 1.87, p < 0.001). The percentage of the population aged 0-14 years, number of health workers per capital, and number of passengers were found to be positively associated with the incidence of mumps. Overall, after 2012, the incidence of mumps in mainland China remained stable. High-risk periods, clusters of regions, and sociodemographic factors for mumps were identified, which will help the government develop the disease- and location-specific interventive measures.

Keywords: epidemiology; mainland China; mumps; sociodemographic factors.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The incidence of mumps in mainland China from 2004 to 2018. (A) The average annual incidence of mumps from 2004 to 2018. (B) The AAPC of mumps from 2004 to 2018.
Figure 2
Figure 2
The seasonal and age group distribution of mumps from 2004 to 2018. (A) The seasonal distribution of mumps from 2004 to 2018. (B) The seasonal and age group distribution of mumps from 2004 to 2018.
Figure 3
Figure 3
The trends of incidence of mumps at different economic levels from 2004 to 2018. (A) The trends of incidence of mumps in mainland China from 2004 to 2018. (B) The trends of incidence of mumps in developed regions from 2004 to 2018. (C) The trends of incidence of mumps in intermediately developed regions from 2004 to 2018. (D) The trends of incidence of mumps in undeveloped regions from 2004 to 2018.
Figure 4
Figure 4
Space–time cluster of mumps in mainland China from 2004 to 2018
See this image and copyright information in PMC

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