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Review
. 2022 Jun 2;9(6):826.
doi: 10.3390/children9060826.

The Etiology and Risk Factors of Osgood-Schlatter Disease: A Systematic Review

Ludovico Lucenti  1 , Marco Sapienza  1 , Alessia Caldaci  1 , Claudia de Cristo  1 , Gianluca Testa  1 , Vito Pavone  1
Affiliations
Review

The Etiology and Risk Factors of Osgood-Schlatter Disease: A Systematic Review

Ludovico Lucenti et al. Children (Basel). .

Abstract

The etiology and etiopathogenesis of Osgood-Schlatter Disease (OD) are not fully understood. The aim of this review is to systematically analyze the available literature about the etiology and risk factors of OD. The literature was systematically reviewed using the PRISMA criteria to evaluate all studies published in the last 25 years (between 1996 and 2021) dealing with the etiology of OD. A total of 16 articles were included. The etiology and risk factors of OD are controversial. The main articles focused on muscular factors (mainly tightness of the rectus femoris), alteration of the patellar tendon or extensor mechanism, mechanical factors (repetitive solicitation, trauma, sports), tibial anatomy (tibial slope or tibial torsion), and histological alteration. Associations with ankle kinematic and behavior disorders were also reported. Many theories about the etiology, risk factors, and associated factors of OD have been reported in the literature, but more studies are needed to fully understand the etiopathogenesis of this disorder.

Keywords: Osgood–Schlatter; etiology; pathogenesis; risk factors.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
PRISMA flowchart.
See this image and copyright information in PMC

References

    1. Lohrer H., Nauck T., Schöll J., Zwerver J., Malliaropoulos N. Einsatz der extrakorporalen Stoßwellentherapie bei therapieresistentem M. Schlatter. Sportverletz. Sportschaden. 2012;26:218–222. doi: 10.1055/s-0032-1325478. - DOI - PubMed
    1. Osgood R.B., Mankin H.J. Lesions of the tibial tubercle occurring during adolescence. Clin. Orthop. Relat. Res. 1993;286:4–9. doi: 10.1097/00003086-199301000-00002. - DOI - PubMed
    1. Gholve P.A., Scher D.M., Khakharia S., Widmann R.F., Green D.W. Osgood Schlatter syndrome. Curr. Opin. Pediatr. 2007;19:44–50. doi: 10.1097/MOP.0b013e328013dbea. - DOI - PubMed
    1. Indiran V., Jagannathan D. Osgood–Schlatter Disease. N. Engl. J. Med. 2018;378:e15. doi: 10.1056/NEJMicm1711831. - DOI - PubMed
    1. Nkaoui M., Alouani E.M. Osgood-schlatter disease: Risk of a disease deemed banal. Pan Afr. Med. J. 2017;28:56. doi: 10.11604/pamj.2017.28.56.13185. - DOI - PMC - PubMed

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