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. 1978 Sep;135(3):935-42.
doi: 10.1128/jb.135.3.935-942.1978.

Effect of tsl (thermosensitive suppressor of lex) mutation on postreplication repair in Escherichia coli K-12

A K Ganesan, P C Seawell, D W Mount

Effect of tsl (thermosensitive suppressor of lex) mutation on postreplication repair in Escherichia coli K-12

A K Ganesan et al. J Bacteriol. 1978 Sep.

Abstract

Cells of Escherichia coli K-12 carrying lexA or recA mutations are more sensitive to UV radiation than corresponding wild-type cells and are defective in postreplication repair. Supressor mutations (tsl) have been described previously which increase the UV resistance of lexA uvr+, lexA uvrA, and recAI uvr+ strains, but not the resistance of recA1 uvrA strains. We have studied the effect of the tsl-1 mutation on postreplication repair and find that the enhanced survival conferred by this mutation is correlated with an increased capacity for postreplication repair.

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References

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