Determinants of Prolonged Length of Hospital Stay in Patients with Severe Acute Ischemic Stroke
- PMID: 35743530
- PMCID: PMC9225000
- DOI: 10.3390/jcm11123457
Determinants of Prolonged Length of Hospital Stay in Patients with Severe Acute Ischemic Stroke
Abstract
Objective: Long hospitalizations are associated with a high comorbidity and considerable hospital cost. Admissions of severe acute ischemic stroke are prone to longer hospitalizations. We aimed to explore the issue and method for improving the length of stay.
Methods: From the prospective Stroke Registry between January 2019 and June 2020, acute ischemic strokes with an admission National Institutes of Health Stroke Scale ≥ 15 were identified. Prolonged length-of-stay was defined as in-hospital-stay ≥ 30 days. All clinical characteristics were collected, and all do-not-resuscitate documentations were categorized if the order had been written within 7 days of onset.
Results: A total of 212 patients were eligible for severe stroke. Of these, 42 (19.8%) had prolonged length-of-stay and 170 had non-prolonged length-of-stay (median 43 vs. 13 days). The prolonged group was younger, mostly men, and was more likely to be in an independent state and more likely to receive reperfusion therapy, and there was a higher frequency of late do-not-resuscitate orders if signed. Although there was a lower in-hospital mortality rate in the prolonged group (12% vs. 23%), there was a higher proportion with a severe functional state (Modified Rankin Scale = 4-5) among the survivors (97% vs. 87%).
Conclusions: Severe acute ischemic stroke patients with a prolonged length-of-stay were younger, mostly male, more likely to receive reperfusion therapy, less likely to have an early do-not-resuscitate order if signed, and more likely to have poor functional status at discharge, although there was a lower rate of in-hospital mortality.
Keywords: do-not-resuscitate; functional outcome; length of hospital stay; prolonged length of stay; severe acute ischemic stroke.
Conflict of interest statement
The authors declare no conflict of interest.
Figures
Similar articles
-
Risk factor identification and prediction models for prolonged length of stay in hospital after acute ischemic stroke using artificial neural networks.Front Neurol. 2023 Feb 9;14:1085178. doi: 10.3389/fneur.2023.1085178. eCollection 2023. Front Neurol. 2023. PMID: 36846116 Free PMC article.
-
[Prolonged factors of length of hospital stay in acute ischemic stroke].Rinsho Shinkeigaku. 2005 Jun;45(6):405-10. Rinsho Shinkeigaku. 2005. PMID: 16022463 Japanese.
-
Prolonged Hospital Length of Stay Does Not Improve Functional Outcome in Acute Ischemic Stroke.Neurol Ther. 2025 Apr;14(2):593-607. doi: 10.1007/s40120-025-00712-2. Epub 2025 Feb 18. Neurol Ther. 2025. PMID: 39964661 Free PMC article.
-
Evaluation of anticoagulation status for atrial fibrillation on early ischaemic stroke outcomes: a registry-based, prospective cohort study of acute stroke care in Surrey, UK.BMJ Open. 2017 Dec 14;7(12):e019122. doi: 10.1136/bmjopen-2017-019122. BMJ Open. 2017. PMID: 29247109 Free PMC article.
-
Association between out-of-hospital emergency department transfer and poor hospital outcome in critically ill stroke patients.J Crit Care. 2011 Dec;26(6):620-5. doi: 10.1016/j.jcrc.2011.02.009. Epub 2011 May 18. J Crit Care. 2011. PMID: 21596517
Cited by
-
Early versus delayed antihypertensive treatment in patients with acute ischaemic stroke: multicentre, open label, randomised, controlled trial.BMJ. 2023 Oct 9;383:e076448. doi: 10.1136/bmj-2023-076448. BMJ. 2023. PMID: 37813418 Free PMC article. Clinical Trial.
-
Predictors of Hospital Stay After Acute Ischemic Stroke in Hospitalized Patients: Retrospective-Cohort Study.Cardiol Res Pract. 2025 May 5;2025:7598035. doi: 10.1155/crp/7598035. eCollection 2025. Cardiol Res Pract. 2025. PMID: 40364818 Free PMC article.
-
Treatment of acute ischemic stroke in patients with active malignancy: insight from a comprehensive stroke center.Ther Adv Neurol Disord. 2023 Oct 31;16:17562864231207508. doi: 10.1177/17562864231207508. eCollection 2023. Ther Adv Neurol Disord. 2023. PMID: 37920861 Free PMC article.
-
Risk factor identification and prediction models for prolonged length of stay in hospital after acute ischemic stroke using artificial neural networks.Front Neurol. 2023 Feb 9;14:1085178. doi: 10.3389/fneur.2023.1085178. eCollection 2023. Front Neurol. 2023. PMID: 36846116 Free PMC article.
-
Impact of Frailty on Healthcare Outcomes after Cardioembolic Ischaemic Stroke Due to Atrial Fibrillation.Int J Environ Res Public Health. 2024 Feb 27;21(3):270. doi: 10.3390/ijerph21030270. Int J Environ Res Public Health. 2024. PMID: 38541270 Free PMC article.
References
-
- Marfil-Garza B.A., Belaunzaran-Zamudio P.F., Gulias-Herrero A., Zuniga A.C., Caro-Vega Y., Kershenobich-Stalnikowitz D., Sifuentes-Osornio J. Risk factors associated with prolonged hospital length-of-stay: 18-year retrospective study of hospitalizations in a tertiary healthcare center in Mexico. PLoS ONE. 2018;13:e0207203. - PMC - PubMed
LinkOut - more resources
Full Text Sources