Targeting Subviral Particles: A Critical Step in Achieving HBV Functional Cure but Where Are We with Current Agents in Clinical Development?
- PMID: 35746664
- PMCID: PMC9227515
- DOI: 10.3390/v14061193
Targeting Subviral Particles: A Critical Step in Achieving HBV Functional Cure but Where Are We with Current Agents in Clinical Development?
Abstract
The recent review [...].
Conflict of interest statement
AV is an employee and shareholder of Replicor Inc.
Comment on
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HBsAg Loss as a Treatment Endpoint for Chronic HBV Infection: HBV Cure.Viruses. 2022 Mar 22;14(4):657. doi: 10.3390/v14040657. Viruses. 2022. PMID: 35458387 Free PMC article. Review.
References
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- Gane E., Yuen M.F., Yogaratnam J., Le K., Vuong J., Christopher W., Gohil V., Schwabe C., Agarwal K., Jucov A., et al. Safety, Tolerability and Pharmacokinetics (PK) of Single and Multiple Doses of ALG-010133, an S-antigen Transport Inhibiting Oligonucleotide Polymer (STOPS) for the Treatment of Chronic Hepatitis B. J. Hepatol. 2021;75:S741.
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- Aligos Aligos Halting Further Development of STOPS™ Drug Candidate, ALG-010133. Press Release. 2022. [(accessed on 8 May 2022)]. Available online: https://investor.aligos.com/news-releases/news-release-details/aligos-ha...
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