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Case Reports
. 2022 Jun 21;14(6):e26141.
doi: 10.7759/cureus.26141. eCollection 2022 Jun.

Ivermectin-Induced Acute Psychosis in Patients Infected With COVID-19 Pneumonia

Lokesh Goyal  1 , Ramesh Pandit  2 , Trupti Pandit  3 , Kunal Ajmera  4 , John O Lusins  5 , Shah Islam  6
Affiliations
Case Reports

Ivermectin-Induced Acute Psychosis in Patients Infected With COVID-19 Pneumonia

Lokesh Goyal et al. Cureus. .

Abstract

Coronavirus disease 2019 (COVID-19) pneumonia is an infection of the lungs that causes severe inflammation in the lungs' alveoli. It causes alveoli to fill with fluid, blood clots, and sometimes even pus. Patients who are infected with COVID-19 pneumonia experience severe cough, shortness of breath, fever, fatigue, chest pain, night sweats, chills, loss of appetite, etc. During the initial phase of the COVID-19 pneumonia pandemic, it was thought that ivermectin might be helpful in patients infected with COVID-19 pneumonia, but this was later proven to be false due to its severe risks/side effects. Infectious Disease Society of America (IDSA) suggests against the use of ivermectin for COVID-19 pneumonia. However, some providers continue to use ivermectin as one of the treatments for patients infected with COVID-19 infection. In this case report, we will discuss ivermectin causing acute psychosis in healthy 45- and 51-year-old patients with no known history of any mental health illness.

Keywords: auditory hallucination; covid 19; covid-19 induced psychosis; ivermectin and albendazole; tactile hallucination.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Mild COVID-19 pneumonia, but otherwise normal chest X-ray.
See this image and copyright information in PMC

References

    1. Ivermectin | COVID-19 Treatment Guidelines. [ Jun; 2022 ];https://www.covid19treatmentguidelines.nih.gov/therapies/antiviral-thera... 2022
    1. The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer. Yang SN, Atkinson SC, Wang C, Lee A, Bogoyevitch MA, Borg NA, Jans DA. Antiviral Res. 2020;177:104760. - PubMed
    1. Over 25 years of clinical experience with ivermectin: an overview of safety for an increasing number of indications. Kircik LH, Del Rosso JQ, Layton AM, Schauber J. https://pubmed.ncbi.nlm.nih.gov/26954318/ J Drugs Dermatol. 2016;15:325–332. - PubMed
    1. Ivermectin inhibits LPS-induced production of inflammatory cytokines and improves LPS-induced survival in mice. Zhang X, Song Y, Ci X, et al. Inflamm Res. 2008;57:524–529. - PubMed
    1. Ivermectin may be a clinically useful anti-inflammatory agent for late-stage COVID-19. DiNicolantonio JJ, Barroso J, McCarty M. Open Heart. 2020;7 - PMC - PubMed

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