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Review
. 2022 Aug;62 Suppl 1(Suppl 1):S313-S322.
doi: 10.1111/trf.16961. Epub 2022 Jun 24.

A review of two emerging technologies for pre-hospital treatment of non-compressible abdominal hemorrhage

Brendan M McCracken  1   2 , Kevin R Ward  1   2   3 , Mohamad Hakam Tiba  1   2
Affiliations
Review

A review of two emerging technologies for pre-hospital treatment of non-compressible abdominal hemorrhage

Brendan M McCracken et al. Transfusion. 2022 Aug.
No abstract available

Keywords: GROA; REBOA; abdominal organ injury; aorta; inflatable device; non-compressible hemorrhage; resuscitation; shock.

PubMed Disclaimer

Conflict of interest statement

BMM, KRW, and MHT have intellectual property associated with the devices discussed in this review through the University of Michigan. These technologies have been licensed to Precision Trauma LLC. Kevin R. Ward has equity in the company.

Figures

FIGURE 1
FIGURE 1
Left panel (A); Morphomic analysis of the aorta position in relation to the inferior aspect of the vertebral body of T10 in 1641 war fighter‐aged subjects. The center of the vertebral body in the axial plane is used as the origin. Right panel (B); frequency of the radial position of the aorta with respect to the vertebral body in the same population
FIGURE 2
FIGURE 2
Top left panel; an illustrated version of the GROA device applied to a human; (A) air pump/pressure gauge assembly, (B) gastroesophageal tube (C) ellipsoid shaped gastric balloon, (D) retractable 14F tip. Top right panel; adjustable external compression system. Bottom panel; arterial pressure from the carotid and femoral arteries, and hepatic artery flow during GROA occlusion
FIGURE 3
FIGURE 3
Top left panel; illustration of an automated applicator and intraperitoneal balloon deployment. Top right panel; illustration of the IPHD balloon inflated after intraperitoneal deployment and external pressure being applied for selective aortic occlusion. Bottom panel; arterial pressure from the carotid and femoral arteries, and hepatic artery flow during user‐selected aortic occlusion
FIGURE 4
FIGURE 4
Kaplan Meier plot of survival proportions in a preclinical swine model of rapidly lethal abdominal hemorrhage; GROA (n = 8) and IPHD (n = 5) treated animals are represented as dashed and dotted dashed lines, respectively, and plotted against controls (n = 11) (solid line).
See this image and copyright information in PMC

References

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Publication types