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Multicenter Study
. 2022 Aug 18;140(7):789-792.
doi: 10.1182/blood.2022016818.

Thrombopoietin receptor agonists in adult Evans syndrome: an international multicenter experience

Bruno Fattizzo  1   2 , Nicola Cecchi  1   2 , Marta Bortolotti  1   2 , Giulio Giordano  3 , Andrea Patriarca  4 , Andreas Glenthøj  5 , Silvia Cantoni  6 , Marco Capecchi  1   2 , Frederick Chen  7 , Maria Eva Mingot-Castellano  8 , Mariasanta Napolitano  9 , Henrik Frederiksen  10 , Tomàs José Gonzaléz-Lopez  11 , Wilma Barcellini  1
Affiliations
Multicenter Study

Thrombopoietin receptor agonists in adult Evans syndrome: an international multicenter experience

Bruno Fattizzo et al. Blood. .
No abstract available

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Figures

Figure 1.
Figure 1.
Evaluation of TPO-RA treatment in patients with ES and in a cohort of patients with ITP. (A) PLT counts during treatment in ES. (B) Response rates at various time points in ES. (C) Comparison of outcomes of ES with those of primary ITP. Response rates in ITP were 77% at month +1, 80% at month +3, 88% at month +6, and 92% at month +12.
See this image and copyright information in PMC

References

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    1. Michel M, Chanet V, Dechartres A, et al. . The spectrum of Evans syndrome in adults: new insight into the disease based on the analysis of 68 cases. Blood. 2009;114(15):3167-3172. - PubMed
    1. Fattizzo B, Michel M, Giannotta JA, et al. . Evans syndrome in adults: an observational multicenter study. Blood Adv. 2021;5(24):5468-5478. - PMC - PubMed
    1. Neunert C, Terrell DR, Arnold DM, et al. . American Society of Hematology 2019 guidelines for immune thrombocytopenia [published correction appears in Blood Adv. 2020;4(2):252] Blood Adv. 2019;3(23):3829-3866. - PMC - PubMed
    1. Gonzalez-Nieto JA, Martin-Suarez I, Quattrino S, et al. . The efficacy of romiplostim in the treatment of severe thrombocytopenia associated to Evans syndrome refractory to rituximab. Lupus. 2011;20(12):1321-1323. - PubMed

Publication types

Supplementary concepts