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Review
. 2022 Sep;92(9):2224-2228.
doi: 10.1111/ans.17863. Epub 2022 Jun 25.

Splanchnic venous thrombosis: aetiologies and a review of the literature

Rebekah Tan  1 , Ali Daneshmand  1 , Simon Parys  1 , Yuki Watanabe  1 , Kishore Sieunarine  2
Affiliations
Review

Splanchnic venous thrombosis: aetiologies and a review of the literature

Rebekah Tan et al. ANZ J Surg. 2022 Sep.

Abstract

Background: Splanchnic vein thrombosis (SVT) is an uncommon yet potentially life-threatening manifestation of venous thromboembolism. The aim of this study was to present a retrospective analysis of a cohort of Western Australian patients diagnosed with SVT on imaging study, and a review of the literature surrounding the aetiology, location, anticoagulation treatment and outcomes of SVT.

Methods: All patients diagnosed with SVT over a five-year period from 2015 to 2020 in three tertiary hospitals in Western Australia were identified by using an electronic search engine of imaging reports. Collected data included patient demographics and co-morbidity, presentation data, location of thrombus, aetiology of thrombus, treatment with anti-coagulation, length of stay and outcome data including mortality.

Results: A total of 164 patients met inclusion criteria. The 90-day mortality was 20.1%; 64% of whom were those with portal vein thrombosis. Aetiology was grouped into haematological conditions (4 patients), non-haematological conditions (130 patients), a combination of factors (17 patients) and idiopathic (13 patients). The majority of deaths were due to malignancy, severe pancreatitis or decompensated liver cirrhosis.

Conclusion: Whilst the prevalence of SVT is rising with the increase in accessibility to radiological studies, it remains a diagnostic and therapeutic challenge for clinicians. With no consensus guidelines available to direct treatment, the management of patients with SVT should be individualized and considered carefully. The potential complications of venous thrombosis, SVT recurrence or extension and the risk of bleeding need to be evaluated before the commencement of anticoagulation therapy.

Keywords: aetiologies; literature review; mortality; splanchnic venous thrombosis.

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References

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