Vaccination with fractional doses: promise or illusion?

Affiliations

¹ Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany; Congolese Foundation for Medical Research, Brazzaville, Republic of Congo. Electronic address: fntoumi@fcrm-congo.com.
² Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.

Comment

Francine Ntoumi et al. Lancet Infect Dis. 2022 Sep.

. 2022 Sep;22(9):1258-1259.

doi: 10.1016/S1473-3099(22)00310-3. Epub 2022 Jun 23.

¹ Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany; Congolese Foundation for Medical Research, Brazzaville, Republic of Congo. Electronic address: fntoumi@fcrm-congo.com.
² Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.

No abstract available

Conflict of interest statement

We declare no competing interests.

Efficacy of RTS,S/AS01_E malaria vaccine administered according to different full, fractional, and delayed third or early fourth dose regimens in children aged 5-17 months in Ghana and Kenya: an open-label, phase 2b, randomised controlled trial.
Samuels AM, Ansong D, Kariuki SK, Adjei S, Bollaerts A, Ockenhouse C, Westercamp N, Lee CK, Schuerman L, Bii DK, Osei-Tutu L, Oneko M, Lievens M, Attobrah Sarfo MA, Atieno C, Morelle D, Bakari A, Sang T, Jongert E, Kotoh-Mortty MF, Otieno K, Roman F, Buabeng PBY, Ntiamoah Y, Ofori-Anyinam O, Agbenyega T; RTS,S study group. Samuels AM, et al. Lancet Infect Dis. 2022 Sep;22(9):1329-1342. doi: 10.1016/S1473-3099(22)00273-0. Epub 2022 Jun 23. Lancet Infect Dis. 2022. PMID: 35753316 Free PMC article. Clinical Trial.