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. 2022 Jun 9:9:823067.
doi: 10.3389/fmed.2022.823067. eCollection 2022.

Effects of Early Bedside Cycle Exercise on Gastrointestinal Function in Intensive Care Unit Patients Receiving Mechanical Ventilation

Tingting Yu  1 , Fuliang Cai  1 , Rong Jiang  2
Affiliations

Effects of Early Bedside Cycle Exercise on Gastrointestinal Function in Intensive Care Unit Patients Receiving Mechanical Ventilation

Tingting Yu et al. Front Med (Lausanne). .

Abstract

Background: A prolonged stay in the intensive care unit (ICU) is associated with gastrointestinal failure, which may have a destructive effect on functional status within 1 year after hospital discharge. The aim was to investigate the effects of a daily exercise session, using a bedside cycle ergometer, on gastrointestinal functions, such as diarrhea, gastric retention, and vomiting, in patients with severe pneumonia who received mechanical ventilation (MV).

Methods: The study was a randomized controlled trial, and its setting was the ICU of a tertiary hospital in Eastern China. A total of 102 critically ill patients who received MV were recruited only when their cardiorespiratory function was deemed stable to perform a bedside cycling exercise. Those patients were expected to spend a minimum of 7 days in the ICU. All subjects received respiratory physiotherapy and performed a daily standardized passive or active motion session of their limbs. The patients were randomized into two groups, namely, the treatment group, which were administered passive or active leg exercise intervention for 20 min/day using a bedside ergometer, and the control group, which did not. Gastrointestinal (GI) functions and the nutritional status of both groups were evaluated on the first, fourth, and seventh days of training and at discharge.

Results: During the 7 days of the study, the number of patients with diarrhea in the treatment group was significantly lower than that in the control group. In contrast, there were significantly more patients in the treatment group with increased bowel sounds (P < 0.05). However, there was no significant difference in the number of patients with vomiting and gastric retention between these two groups. Moreover, when the patients were discharged from the hospital, the albumin level and lymphocyte count were significantly higher in the treatment group (P < 0.05). In addition, the number of invasive ventilation days in the treatment group was less than that in the control group (P < 0.05). While the ICU length of stay and the total hospitalization time were not significantly different between the two groups.

Conclusion: Early exercise training in critical ICU survivors who received MV enhanced the recovery of gastrointestinal functions and improved the patient's nutrition status at hospital discharge.

Keywords: critical illness; early bedside cycle exercise; exercise therapy; gastrointestinal failure; mechanical ventilation.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Bedside cycle ergometer (Shandong ZEPU Medical Technology Company, China).
FIGURE 2
FIGURE 2
Flow diagram of the patients admitted to this trial.
FIGURE 3
FIGURE 3
Nutrient status of the patients admitted to this trial. *p < 0.05 compared with control group.
See this image and copyright information in PMC

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