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. 2022 Jan 12:2:141-148.
doi: 10.1016/j.ijregi.2022.01.004. eCollection 2022 Mar.

Prevalence of tuberculosis (TB), including multi-drug-resistant and extensively-drug-resistant TB, and association with occupation in adults at Sirindhorn Hospital, Bangkok

Fingani Annie Mphande-Nyasulu  1 , Paisal Puengpipattrakul  1 , Mathuwadee Praipruksaphan  2 , Arada Keeree  2 , Karakade Ruanngean  2
Affiliations

Prevalence of tuberculosis (TB), including multi-drug-resistant and extensively-drug-resistant TB, and association with occupation in adults at Sirindhorn Hospital, Bangkok

Fingani Annie Mphande-Nyasulu et al. IJID Reg. .

Abstract

Background: Tuberculosis (TB) affects both child and adult populations worldwide.

Objectives: This retrospective study was conducted to survey the prevalence of TB and its association with patient occupation in an adult population diagnosed with TB at Sirindhorn Hospital in 2018.

Methods: Data were extracted from the medical records of 186 patients with TB, and prevalence and odds ratios were calculated.

Results: Pulmonary (83.3%) and extrapulmonary TB (17.7%) were observed among the cases. Overall, 70.4% of cases were male and 29.6% were female. Mono-drug-resistant TB, multi-drug-resistant TB and extensively-drug-resistant TB were observed in 2.72%, 4.1% and 0.68% of cases, respectively. Although not statistically significant, individuals with comorbidities had a 2.16-fold [95% confidence interval (CI) 0.33-13.98] higher risk of TB compared with those without comorbidities. Unemployed patients with TB were 4-fold (95% CI 0.82-19.42) more likely to have hypertension than employed patients or traders. The risk of TB among patients with human immunodeficiency virus (HIV) infection was 2.22-fold (95% CI 0.93-5.31) higher among females compared with males, and relapsed patients had a 0.92-fold (95% CI 0.19-4.47) lower risk of HIV infection as a comorbidity compared with new TB cases.

Conclusion: Patient occupation could play a role in the prevalence of TB among communities. The highest prevalence of TB was observed among unemployed subjects, and unemployed patients with TB were more likely to have hypertension as a comorbidity. Mapping the zones/areas of residence for patients with TB could assist in identifying TB hot spots, and could improve understanding of the drivers of the high TB burden and associated socio-economic factors. More studies are required to further understand the drivers that are leading to the high TB burden and the risks posed by occupations.

Keywords: Diabetes; Hypertension; Occupation (livelihood); Pulmonary tuberculosis; Socio-economic factors.

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Figures

Figure 1
Figure 1
Tuberculosis comorbidities among new and relapsed cases. CVA, cerebrovascular accident; COPD, chronic obstructive pulmonary disease; HBV, hepatitis B virus infection; DLP, dyslipidaemia; HIV, human immunodeficiency virus infection; DM, diabetes mellitus; HT, hypertension.
Figure 2
Figure 2
Distribution of tuberculosis (TB) cases by city/town of residence attending Sirindhorn Hospital in 2018. DR-TB, mono-drug-resistant TB; MDR-TB, multi-drug-resistant TB; XDR-TB, extensively-drug-resistant TB.
Figure 3
Figure 3
Occupations of tuberculosis (TB patients) attending Sirindhorn Hospital in 2018.
See this image and copyright information in PMC

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