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Review
. 2022 Jun 10:13:880201.
doi: 10.3389/fimmu.2022.880201. eCollection 2022.

Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review

Jin Bu  1 , Ruilian Ding  1 , Liangjia Zhou  1 , Xiangming Chen  2 , Erxia Shen  2   3
Affiliations
Review

Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review

Jin Bu et al. Front Immunol. .

Abstract

Psoriasis is a chronic autoimmune inflammatory disease that remains active for a long period, even for life in most patients. The impact of psoriasis on health is not only limited to the skin, but also influences multiple systems of the body, even mental health. With the increasing of literature on the association between psoriasis and extracutaneous systems, a better understanding of psoriasis as an autoimmune disease with systemic inflammation is created. Except for cardiometabolic diseases, gastrointestinal diseases, chronic kidney diseases, malignancy, and infections that have received much attention, the association between psoriasis and more systemic diseases, including the skin system, reproductive system, and oral and ocular systems has also been revealed, and mental health diseases draw more attention not just because of the negative mental and mood influence caused by skin lesions, but a common immune-inflammatory mechanism identified of the two systemic diseases. This review summarizes the epidemiological evidence supporting the association between psoriasis and important and/or newly reported systemic diseases in the past 5 years, and may help to comprehensively recognize the comorbidity burden related to psoriasis, further to improve the management of people with psoriasis.

Keywords: autoimmune chronic diseases; comorbid disease; epidemiology; prevalence; psoriasis disease.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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