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. 2022 Sep;144(3):579-583.
doi: 10.1007/s00401-022-02455-y. Epub 2022 Jun 27.

Intratumor and informatic heterogeneity influence meningioma molecular classification

Harish N Vasudevan  1   2 , Abrar Choudhury #  1   2 , Stephanie Hilz #  2 , Javier E Villanueva-Meyer  3 , William C Chen  1   2 , Calixto-Hope G Lucas  4 , Steve E Braunstein  1 , Nancy Ann Oberheim Bush  2 , Nicholas Butowski  2   5 , Melike Pekmezci  4 , Michael W McDermott  6 , Arie Perry  2   4 , David A Solomon  4 , Stephen T Magill #  7 , David R Raleigh #  8   9
Affiliations

Intratumor and informatic heterogeneity influence meningioma molecular classification

Harish N Vasudevan et al. Acta Neuropathol. 2022 Sep.
No abstract available

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Conflict of interest statement

Conflict of interest The authors declare they have no competing interests related to this study.

Figures

Fig. 1
Fig. 1
Intratumor and informatic heterogeneity influence meningioma molecular classification. a 3D stereotactic meningioma sampling maps reconstructed from preoperative magnetic resonance imaging. b Meningioma sample purity across DNA methylation groups. c Intratumor phylogenies based on clonal ordering of CNVs derived from meningioma DNA methylation profiling. d CNV phylogenies based on meningioma RNA sequencing. e CNVs derived from DNA methylation profiling and allelic frequency derived from targeted DNA sequencing of meningioma M8E. f CNVs derived from DNA methylation profiling of meningioma MSC6. g Uniform manifold approximation and projection of MSC6 single-cell RNA sequencing transcriptomes
See this image and copyright information in PMC

References

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