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Review
. 2022 Oct;25(5):705-708.
doi: 10.1007/s11102-022-01241-z. Epub 2022 Jun 27.

Biochemical testing to differentiate Cushing's disease from ectopic ACTH syndrome

Amandine Ferriere  1 , Antoine Tabarin  2
Affiliations
Review

Biochemical testing to differentiate Cushing's disease from ectopic ACTH syndrome

Amandine Ferriere et al. Pituitary. 2022 Oct.

Abstract

The differential diagnosis of ACTH-dependent Cushing's syndrome is often a diagnostic challenge that has been debated in numerous studies. In this short article, we will discuss the performance and main drawbacks of the biochemical tests used for this diagnosis.

Keywords: CRH test; Cushing’s disease; Desmopressin test; Dexamethasone suppression test; Ectopic ACTH syndrome; Inferior petrosal sinus sampling.

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