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. 2022 Sep;50(9):1060-1063.
doi: 10.1016/j.ajic.2022.06.018. Epub 2022 Jun 26.

COVID-19 clusters in a teaching hospital during the second wave of the SARS-CoV-2 pandemic in France: A descriptive study and lessons learned for waves to come

Cédric Dananché  1 , Christelle Elias  2 , Nicolas Guibert  3 , Sophie Gardes  4 , Christine Barreto  4 , Marie-Agnès Denis  3 , Pascal Fascia  4 , Solweig Gerbier  4 , Béatrice Grisi  4 , Nagham Khanafer  2 , Amélie Massardier-Pilonchéry  3 , Élodie Munier-Marion  4 , Claudine Pasquet  5 , Jean-Baptiste Fassier  3 , Philippe Vanhems  6
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COVID-19 clusters in a teaching hospital during the second wave of the SARS-CoV-2 pandemic in France: A descriptive study and lessons learned for waves to come

Cédric Dananché et al. Am J Infect Control. 2022 Sep.

Abstract

A total of 92 coronavirus disease 2019 clusters involving 1,156 individuals (729 patients and 427 healthcare workers) occurred in Lyon University Hospital between September 1, 2020 and March 31, 2021, mostly on medical and geriatric wards. The number of clusters was closely correlated to the trend in coronavirus disease 2019 community incidence over time; in-hospital clusters did not persist when community incidence decreased. Recommended preventive measures were not fully applicable due to specific ward-associated determinants and patient characteristics.

Keywords: COVID-19; Cluster; Community incidence; Healthcare-associated infection; SARS-CoV-2.

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Figures

Fig 1
Fig 1
Description of healthcare-associated COVID-19 clusters occurring weekly in Lyon University Hospitals between September 1, 2020 and March 31, 2021. The black line represents the community incidence of COVID-19 in the Grand Lyon area (total new COVID-19 cases per 100,000 population in the past 7 days). The dark grey columns represent the cumulative number of patients infected in the COVID-19 clusters by week; the light grey columns represent the cumulative number of HCWs infected in the COVID-19 clusters by week. The black columns on the lower side of the Figure represent the number of clusters by week.
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