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. 2022 Sep:122:531-533.
doi: 10.1016/j.ijid.2022.06.033. Epub 2022 Jun 26.

Caution when using 1,3, β-D-glucan in the CSF as a biomarker of Candida albicans meningitis

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Free article

Caution when using 1,3, β-D-glucan in the CSF as a biomarker of Candida albicans meningitis

Laura Barbolini et al. Int J Infect Dis. 2022 Sep.
Free article

Abstract

Relying on a biomarker to diagnose or follow up the treatment of a Candida albicans meningitis would have an impact on patient management. The biomarker 1,3, β-D-glucan (BDG), developed for serum testing, shows inconsistent values when applied on cerebrospinal fluid (CSF), and its use with the current protocol on CSF samples warrants caution.

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Conflict of interest statement

Conflicts of interest The authors have no competing interests to declare.

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