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. 2022 Sep;57(9):1464-1467.
doi: 10.1038/s41409-022-01745-z. Epub 2022 Jun 27.

Cyclophosphamide induced haemorrhagic myocarditis-pericarditis: a rare but lethal complication in the setting of allogeneic stem cell transplantation

Sushil Selvarajan  1 , Spandana Tammiraju  2 , Sharon Lionel  2 , Uday Kulkarni  2 , Priyatesh Chandra Dwivedi  2 , Fouzia Aboobacker  2 , Anu Korula  2 , Aby Abraham  2 , Vikram Mathews  2 , Alok Srivastava  2 , Pratheesh George  3 , John Jose  3 , Thomas Alex Kodiatte  4 , Elizabeth Joseph  5 , Biju George  6
Affiliations

Cyclophosphamide induced haemorrhagic myocarditis-pericarditis: a rare but lethal complication in the setting of allogeneic stem cell transplantation

Sushil Selvarajan et al. Bone Marrow Transplant. 2022 Sep.
No abstract available

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References

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    1. Kohn FR, Sladek NE. Aldehyde dehydrogenase activity as the basis for the relative insensitivity of murine pluripotent hematopoietic stem cells to oxazaphosphorines. Biochem Pharm. 1985;34:3465–71. - DOI
    1. Goldberg MA, Antin JH, Guinan EC, Rappeport JM. Cyclophosphamide cardiotoxicity: an analysis of dosing as a risk factor. Blood. 1986;68:1114–8. - DOI
    1. Yeh J, Whited L, Saliba RM, Rondon G, Banchs J, Shpall E, et al. Cardiac toxicity after matched allogeneic hematopoietic cell transplant in the posttransplant cyclophosphamide era. Blood Adv. 2021;5:5599–607. - DOI
    1. Appelbaum F, Strauchen J, Graw R, Savage D, Kent K, Ferrans V, et al. Acute lethal carditis caused by high-dose combination chemotherapy: a unique clinical and pathological entity. Orig Publ. 1976;307:58–62.

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