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Comment
. 2022 Aug;23(8):459.
doi: 10.1038/s41576-022-00517-1.

Genome-scale single-cell CRISPR screens

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Comment

Genome-scale single-cell CRISPR screens

Lucia Brunello. Nat Rev Genet. 2022 Aug.
No abstract available

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  • Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
    Replogle JM, Saunders RA, Pogson AN, Hussmann JA, Lenail A, Guna A, Mascibroda L, Wagner EJ, Adelman K, Lithwick-Yanai G, Iremadze N, Oberstrass F, Lipson D, Bonnar JL, Jost M, Norman TM, Weissman JS. Replogle JM, et al. Cell. 2022 Jul 7;185(14):2559-2575.e28. doi: 10.1016/j.cell.2022.05.013. Epub 2022 Jun 9. Cell. 2022. PMID: 35688146 Free PMC article.

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Original article
    1. Replogle, J. M. et al. Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq. Cell https://doi.org/10.1016/j.cell.2022.05.013 (2022) - DOI - PubMed
Related article
    1. Przybyla, L. & Gilbert, L. A. A new era in functional genomics screens. Nat. Rev. Genet. 23, 89–103 (2022) - DOI

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