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Editorial
. 2022 Sep 1;106(9):1720-1723.
doi: 10.1097/TP.0000000000004197. Epub 2022 Jun 28.

Expert Opinion Special Feature: Patient Selection for Initial Clinical Trials of Pig Organ Transplantation

Richard N Pierson 3rd  1 , James S Allan, David K C Cooper, David A D'Alessandro, Jay A Fishman, Tatsuo Kawai, Gregory D Lewis, Joren C Madsen, James F Markmann, Leonardo V Riella
Affiliations
Editorial

Expert Opinion Special Feature: Patient Selection for Initial Clinical Trials of Pig Organ Transplantation

Richard N Pierson 3rd et al. Transplantation. .
No abstract available

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Conflict of interest statement

D.K.C.C., J.F.M., and J.A.F. are consultants to eGenesis Bio, Cambridge, MA. The other authors declare no conflicts of interest.

Figures

FIGURE 1.
FIGURE 1.
Percentage survival of ESRD patients by treatment modality in 2010 (reproduced with permission from Cooper et al), and based on data from 2 sources (i) USRDS, and (ii) Orandi BJ et al. ESRD, end-stage renal disease.
See this image and copyright information in PMC

References

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    1. Ma D, Hirose T, Lassiter G, et al. Kidney transplantation from tripleknockout pigs expressing multiple human proteins in cynomolgus macaques. Am J Transplant. 2022;22:46–57. - PMC - PubMed
    1. Längin M, Mayr T, Reichart B, et al. Consistent success in life-supporting porcine cardiac xenotransplantation. Nature. 2018;564:430–433. - PubMed
    1. Cleveland DC, Jagdale A, Carlo WF, et al. The genetically engineered heart as a bridge to allotransplantation in infants: just around the corner? Ann Thorac Surg. 2022;114:536–544. - PubMed
    1. Goerlich CE, Griffith B, Hanna P et al. The growth of xenotransplanted hearts can be reduced with growth hormone receptor knockout pig donors. J Thorac Cardiovasc Surg. [Epub ahead of print. September 4, 2021]. doi:10.1016/j.jtcvs.2021.07.051 - DOI - PMC - PubMed

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