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Editorial

. 2022 Sep 1;206(5):530-532.

doi: 10.1164/rccm.202205-0914ED.

From Biomarker to Mechanism? F2-isoprostanes in Pulmonary Fibrosis

Thomas H Thatcher¹, Marc Peters-Golden²

Affiliations

Affiliations

¹ Department of Internal Medicine Virginia Commonwealth University Richmond, Virginia.
² Department of Internal Medicine University of Michigan Medical School Ann Arbor Michigan.

PMID: 35763804
PMCID: PMC9716893
DOI: 10.1164/rccm.202205-0914ED

Editorial

From Biomarker to Mechanism? F2-isoprostanes in Pulmonary Fibrosis

Thomas H Thatcher et al. Am J Respir Crit Care Med. 2022.

. 2022 Sep 1;206(5):530-532.

doi: 10.1164/rccm.202205-0914ED.

Authors

Thomas H Thatcher¹, Marc Peters-Golden²

Affiliations

¹ Department of Internal Medicine Virginia Commonwealth University Richmond, Virginia.
² Department of Internal Medicine University of Michigan Medical School Ann Arbor Michigan.

PMID: 35763804
PMCID: PMC9716893
DOI: 10.1164/rccm.202205-0914ED

No abstract available

PubMed Disclaimer

Comment on

Thromboxane-Prostanoid Receptor Signaling Drives Persistent Fibroblast Activation in Pulmonary Fibrosis.
Suzuki T, Kropski JA, Chen J, Carrier EJ, Chen X, Sherrill TP, Winters NI, Camarata JE, Polosukhin VV, Han W, Rathinasabapathy A, Gutor S, Gulleman P, Sabusap C, Banovich NE, Tanjore H, Freeman ML, Tada Y, Young LR, Gokey JJ, Blackwell TS, West JD. Suzuki T, et al. Am J Respir Crit Care Med. 2022 Sep 1;206(5):596-607. doi: 10.1164/rccm.202106-1503OC. Am J Respir Crit Care Med. 2022. PMID: 35728047 Free PMC article.

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References

1. Comporti M, Signorini C, Arezzini B, Vecchio D, Monaco B, Gardi C. F2-isoprostanes are not just markers of oxidative stress. Free Radic Biol Med . 2008;44:247–256. - PubMed
1. Malli F, Bardaka F, Tsilioni I, Karetsi E, Gourgoulianis KI, Daniil Z. 8-isoprostane levels in serum and bronchoalveolar lavage in idiopathic pulmonary fibrosis and sarcoidosis. Food Chem Toxicol . 2013;61:160–163. - PubMed
1. Chow S, Thomas PS, Malouf M, Yates DH. Exhaled breath condensate (EBC) biomarkers in pulmonary fibrosis. J Breath Res . 2012;6:016004. - PubMed
1. Arezzini B, Vecchio D, Signorini C, Stringa B, Gardi C. F2-isoprostanes can mediate bleomycin-induced lung fibrosis. Free Radic Biol Med . 2018;115:1–9. - PubMed
1. Ting HJ, Khasawneh FT. Platelet function and Isoprostane biology. Should isoprostanes be the newest member of the orphan-ligand family? J Biomed Sci . 2010;17:24. - PMC - PubMed

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