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Multicenter Study
. 2022 Nov;36(11):8047-8059.
doi: 10.1007/s00464-022-09245-3. Epub 2022 Jun 28.

Comparison of long-term outcomes after robotic versus laparoscopic radical gastrectomy: a propensity score-matching study

Jin-Tao Li #  1   2 , Jian-Xian Lin #  1   2 , Fu-Hai Wang  1   2 , Jia-Bin Wang  1   2 , Jun Lu  1   2 , Qi-Yue Chen  1   2 , Long-Long Cao  1   2 , Mi Lin  1   2 , Ru-Hong Tu  1   2 , Ze-Ning Huang  1   2 , Ju-Li Lin  1   2 , Hua-Long Zheng  1   2 , Chao-Hui Zheng  3   4 , Chang-Ming Huang  5   6 , Ping Li  7   8
Affiliations
Multicenter Study

Comparison of long-term outcomes after robotic versus laparoscopic radical gastrectomy: a propensity score-matching study

Jin-Tao Li et al. Surg Endosc. 2022 Nov.

Abstract

Objective: There is insufficient evidence to evaluate the long-term outcomes of robotic radical gastrectomy. The aim of this study was to compare the radical results and long-term outcomes of robotic and laparoscopic radical gastrectomy.

Methods: We prospectively collected and retrospectively analyzed the general clinicopathological data of gastric cancer patients treated with robotic radical gastrectomy (RG) and laparoscopic radical gastrectomy (LG) from July 2016 to July 2018 at Fujian Medical University Union Hospital. The RG cohort was matched 1:3 with the LG cohort by using propensity score matching (PSM). The primary endpoints of the study were 3-year overall survival (OS) and 3-year relapse-free survival (RFS).

Results: The study included 221 patients treated with RG and 1106 patients treated with LG for gastric cancer. After PSM, 211 patients were included in the RG cohort, and 663 patients were included in the LG cohort. The 3-year OS rate was 81.0% in the robotic cohort and 79.3% in the laparoscopic cohort (log-rank test, P = 0.516). The 3-year RFS rate was 78.7% in the robotic cohort and 75.6% in the laparoscopic cohort (log-rank test, P = 0.600). In the subgroup analyses, no significant differences were noted between the RG and LG cohorts in terms of 3-year OS and 3-year RFS (all P > 0.05). The therapeutic value index of each lymph node station dissection in the robotic cohort was comparable to that in the laparoscopic cohort.

Conclusion: Robotic radical gastrectomy can achieve radical results and long-term outcomes comparable to laparoscopic surgery, and further multicenter prospective studies can be conducted to assess the clinical efficacy of robotic radical gastrectomy.

Keywords: Gastric cancer; Long-term outcomes; Propensity score matching; Robotic radical gastrectomy; Therapeutic index.

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