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. 2022 Jun 23;9(6):e00789.
doi: 10.14309/crj.0000000000000789. eCollection 2022 Jun.

Diagnosis of Rosai-Dorfman Disease by Upper Endoscopic Ultrasound-Guided Fine-Needle Biopsy

Austin Gable  1 , Thomas Mellor  2 , Andrew Peacock  3 , Devon Mahoney  4 , Preston Gable  5 , R Daniel Lawson  2
Affiliations

Diagnosis of Rosai-Dorfman Disease by Upper Endoscopic Ultrasound-Guided Fine-Needle Biopsy

Austin Gable et al. ACG Case Rep J. .
No abstract available

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Figures

Figure 1.
Figure 1.
Contrasted axial chest computed tomography image showing a large (8.1 cm anterior-posterior × 12.1 cm craniocaudal) posterior mediastinal, paravertebral soft-tissue mass (green arrows) encasing the descending thoracic aorta without luminal compression. The mass abuts the posterior esophageal wall and anteriorly displaces the esophagus.
Figure 2.
Figure 2.
(A) Endoscopic ultrasound demonstrating a lobular, heterogeneous mass with calcifications. (B) Doppler ultrasound showing multiple small vessels abutting the esophagus, heart, aorta, celiac trunk, and superior mesenteric artery without invasion. Fine-needle biopsy of the mass was obtained.
Figure 3.
Figure 3.
Emperipolesis (black arrows), a common finding in Rosai-Dorfman disease, evidenced by histiocyte nuclei flanked by lymphoplasmacytic cells located within the finely stranded histiocytic cytoplasm seen in this patient's endoscopic ultrasound–guided biopsy sample.
See this image and copyright information in PMC

References

    1. Abla O, Jacobsen E, Picarsic J, et al. . Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease. Blood. 2018;131(26):2877–90. - PMC - PubMed
    1. Ioannidis I, Manolakis C, Laurini JA, et al. . Rectal extranodal Rosai-Dorfman disease diagnosed by EUS-FNA: A case report and review of the literature. Diagn Cytopathol. 2015;43(1):40–4. - PubMed