Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2022 Jun;50(6):3000605221108047.
doi: 10.1177/03000605221108047.

Evaluation of clinical efficacy of continuous care with improved insulin injection techniques on patients with diabetes mellitus: a randomized controlled trial

Affiliations
Randomized Controlled Trial

Evaluation of clinical efficacy of continuous care with improved insulin injection techniques on patients with diabetes mellitus: a randomized controlled trial

Fang-Ying Zhang et al. J Int Med Res. 2022 Jun.

Abstract

Objective: To investigate the clinical effect of continuous care with improved insulin injection techniques on patients with diabetes mellitus.

Methods: This randomized controlled trial enrolled patients with diabetes mellitus. They were randomly assigned to a control or observation group. Patients in the control group received conventional continuous nursing. Patients in the observation group were given optimized insulin injection education and continuous nursing on the same basis as the conventional nursing used in the control group. Blood glucose-related outcomes, knowledge of insulin injections and adverse events were recorded.

Results: A total of 96 patients with diabetes mellitus were enrolled in the study (n = 48 per group). There were no significant differences between the two groups in terms of sex, age and glycosylated haemoglobin (HbA1c). Compared with the control group, continuous care combined with optimized insulin injection techniques significantly reduced blood glucose target time, fasting blood glucose, 2-h postprandial blood glucose and HbA1c. The proportions of patients reporting a subcutaneous mass, insulin leakage and hypoglycaemic events were significantly lower in the observation group; and pain scores were significantly reduced compared with the control group.

Conclusions: Continuous care and optimization of insulin injection techniques can help patients achieve better diabetes-related outcomes.Study Registration Number: ChiCTR2200057166.

Keywords: Continuity care; clinical efficacy; diabetes; insulin injection techniques.

PubMed Disclaimer

Conflict of interest statement

Declaration of conflicting interest: The authors declare that there are no conflicts of interest.

Figures

Figure 1.
Figure 1.
Flow chart showing progress through enrolment, randomization and analysis of patients with diabetes mellitus that were enrolled in a study to investigate the clinical effect of improved insulin injection techniques in the treatment of diabetes mellitus under the guidance of continuous nursing. WHO, World Health Organization.

Similar articles

References

    1. Strain WD, Paldánius PM. Diabetes, cardiovascular disease and the microcirculation. Cardiovasc Diabetol 2018; 17: 57. - PMC - PubMed
    1. Nanayakkara N, Ranasinha S, Gadowski A, et al.. Age, age at diagnosis and diabetes duration are all associated with vascular complications in type 2 diabetes. J Diabetes Complications 2018; 32: 279–290. - PubMed
    1. Viigimaa M, Sachinidis A, Toumpourleka M, et al.. Macrovascular complications of type 2 diabetes mellitus. Curr Vasc Pharmacol 2020; 18: 110–116. - PubMed
    1. Posner BI. Insulin signalling: the inside story. Can J Diabetes 2017; 41: 108–113. - PMC - PubMed
    1. Zhang Y, Yu J, Kahkoska AR, et al. . Advances in transdermal insulin delivery. Adv Drug Deliv Rev; 139: 51–70. - PMC - PubMed

Publication types