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Published Erratum
. 2022 Jun 29;79(7):388.
doi: 10.1007/s00018-022-04418-8.

Correction: Inflammation and neutrophil extracellular traps in cerebral cavernous malformation

Anthony C Y Yau  1 , Maria Ascencion Globisch  1 , Favour Chinyere Onyeogaziri  1 , Lei L Conze  1 , Ross Smith  1 , Suvi Jauhiainen  1 , Monica Corada  2 , Fabrizio Orsenigo  2 , Hua Huang  1 , Melanie Herre  3 , Anna-Karin Olsson  3 , Matteo Malinverno  2 , Veronica Sundell  1 , Behnam Rezai Jahromi  4 , Mika Niemelä  4 , Aki Laakso  4 , Cecilia Garlanda  5   6 , Alberto Mantovani  5   6   7 , Maria Grazia Lampugnani  2   8 , Elisabetta Dejana  1   2 , Peetra U Magnusson  9
Affiliations
Published Erratum

Correction: Inflammation and neutrophil extracellular traps in cerebral cavernous malformation

Anthony C Y Yau et al. Cell Mol Life Sci. .
No abstract available

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Figures

Fig. 1
Fig. 1
RNA-Seq analysis showed increased expression of inflammation-related genes in brain microvascular endothelial cells from Ccm3iECKO mice (CCM3) in acute and chronic CCM. A Schematic diagram of the experimental design of the transcriptomic study in acute and chronic CCM, comparing CCM3 mice and wild-type (WT) mice (n = 3 per group in acute CCM, n = 5 in chronic CCM). B RNA-Seq gene expression analysis of up-regulated genes showing the top 20 most enriched gene ontology (GO) terms in acute (left panel) and chronic (right panel) CCM. Immune-related GO terms are given in bold. *Regulation of extrinsic apoptotic signaling pathway via death domain receptors, **adaptive immune responses based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, # protein-DNA complex subunit organisation. C Bar plots for the numbers of CCM-associated immune genes that were up-regulated or down-regulated (DEGs) in acute (left) and chronic (right) CCM. For definition of immune genes, see Methods. D Heatmap showing the expression levels (Z-score of regularized log (rlog)-transformed counts) of significantly up-regulated DEGs (padj < 0.05 & |log2foldchange|> 0.5; blue: low; red: high) in both acute (upper panel) and chronic (lower panel) models. The first annotation column to the right indicates differential expression in log2 fold changes (red: high; white: low). The second to seventh annotation columns indicates the DEGs associated with enriched immune-like GO terms (stated at the top of the figure) from over-representation analysis. Some of the genes labelled after annotation columns were discussed in the text
See this image and copyright information in PMC

Erratum for

  • Inflammation and neutrophil extracellular traps in cerebral cavernous malformation.
    Yau ACY, Globisch MA, Onyeogaziri FC, Conze LL, Smith R, Jauhiainen S, Corada M, Orsenigo F, Huang H, Herre M, Olsson AK, Malinverno M, Sundell V, Rezai Jahromi B, Niemelä M, Laakso A, Garlanda C, Mantovani A, Lampugnani MG, Dejana E, Magnusson PU. Yau ACY, et al. Cell Mol Life Sci. 2022 Mar 25;79(4):206. doi: 10.1007/s00018-022-04224-2. Cell Mol Life Sci. 2022. PMID: 35333979 Free PMC article.

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