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Case Reports
. 2022 Jun 21;10(6):e5979.
doi: 10.1002/ccr3.5979. eCollection 2022 Jun.

A rare new presentation of pemphigus vulgaris

Nikoo Mozafari  1 , Raziyeh Ganji  1 , Parviz Toossi  1
Affiliations
Case Reports

A rare new presentation of pemphigus vulgaris

Nikoo Mozafari et al. Clin Case Rep. .

Abstract

We report a new presentation for pemphigus vulgaris in a 51-year-old female patient that was complaining only from non-healing foot ulcer, but unfortunately pemphigus was not confirmed and the patient lost multiple nails. This new variation is reported to increase health workers' awareness especially in races pemphigus seems to be common.

Keywords: mucocutaneous manifestations; pemphigus; pemphigus vulgaris.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

FIGURE 1
FIGURE 1
(A and B) Ulcerated plaques with elevated borders. (C) Erythematous erosion on the inner aspect of lower lip
FIGURE 2
FIGURE 2
Intercellular deposits of IgG within the epidermis
FIGURE 3
FIGURE 3
Complete resolution of skin and oral lesions 4 months after starting therapy
See this image and copyright information in PMC

References

    1. Vodo D, Sarig O, Sprecher E. The genetics of pemphigus vulgaris. Front Med (Lausanne). 2018;5:226. doi: 10.3389/fmed.2018.00226 - DOI - PMC - PubMed
    1. Melchionda V, Harman KE. Pemphigus vulgaris and pemphigus foliaceus: an overview of the clinical presentation, investigations and management. Clin Exp Dermatol. 2019;44(7):740‐746. doi: 10.1111/ced.14041 - DOI - PubMed
    1. Daltaban Ö, Özçentik A, Akman Karakaş A, Üstün K, Hatipoğlu M, Uzun S. Clinical presentation and diagnostic delay in pemphigus vulgaris: a prospective study from Turkey. J Oral Pathol Med. 2020;49(7):681‐686. doi: 10.1111/jop.13052 - DOI - PubMed
    1. A M. Pemphigus. In: Bolognia JL, Schaffer JV, Cerroni L, eds. Dermatology. Vol 2. 4th ed. Elsevier; 2018:494‐509.
    1. Hicham T, Chahnoun FZ, Hanafi T, Hjira N, Mohammed B. Pemphigus vulgaris: a clinical study of 31 cases (2004–2014) in Morocco. Dermatol Res Pract. 2020;2020:8535109. doi: 10.1155/2020/8535109 - DOI - PMC - PubMed

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