Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Jun 30;48(3):133-148.
doi: 10.5125/jkaoms.2022.48.3.133.

A systematic review of treatment and outcomes in patients with mandibular coronoid process hyperplasia

Griet I L Parmentier  1 , Margaux Nys  1 , Laurence Verstraete  1 , Constantinus Politis  1
Affiliations
Review

A systematic review of treatment and outcomes in patients with mandibular coronoid process hyperplasia

Griet I L Parmentier et al. J Korean Assoc Oral Maxillofac Surg. .

Abstract

Treatment of mandibular coronoid process hyperplasia (MCPH) has been described and explored in the literature. This systematic review aims to provide a comprehensive overview of the surgical and non-surgical treatment options for MCPH in pediatric and adult populations. Three databases were searched for treatment of MCPH patients (MEDLINE, Embase, and Web of Science). Two reviewers selected case reports and case series based on titles and abstracts. Finally, 55 studies reporting a total of 127 cases were included for qualitative synthesis and data extraction. The mean age at symptom onset was 15.6 years, while the mean age at diagnosis was 23.5 years. Of the included cases, 83.7% were male, and the condition was bilateral in more than 81% of the cases. Coronoidectomy was performed in 82.7% of the included cases, while coronoidotomy was performed in 3.9% of the cases. In 85.0% of the surgically treated cases, the approach was intraoral. The mean maximal intraoperative mouth opening was 38.1 mm compared with 16.5 mm at diagnosis. The mean maximal postoperative mouth opening was 35.3 mm, and the mean follow-up period was 16.3 months. Maximum mouth opening was achieved intraoperatively, and non-surgical treatment after surgery aims to reduce the risk of relapse. Additional research with a higher level of evidence is necessary to confirm these findings.

Keywords: Hyperplasia; Physical therapy modalities; Surgical procedures; Trismus.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) flowchart of the literature search and study selection process.
See this image and copyright information in PMC

References

    1. Lalitha B, Sridevi NS. Variations in the shape of coronoid process of Indian adult dry human mandibles. Int J Sci Stud. 2016;4:22–5.
    1. Nicholson E, Harvati K. Quantitative analysis of human mandibular shape using three-dimensional geometric morphometrics. Am J Phys Anthropol. 2006;131:368–83. doi: 10.1002/ajpa.20425. https://doi.org/10.1002/ajpa.20425. - DOI - PubMed
    1. Starch-Jensen T, Kjellerup AD. Bilateral elongated mandibular coronoid process and restricted mouth opening: a case report. Open Dent J. 2017;11:670–8. doi: 10.2174/1874210601711010670. https://doi.org/10.2174/1874210601711010670. - DOI - PMC - PubMed
    1. Goh YC, Tan CC, Lim D. Coronoid hyperplasia: a review. J Stomatol Oral Maxillofac Surg. 2020;121:397–403. doi: 10.1016/j.jormas.2019.12.019. https://doi.org/10.1016/j.jormas.2019.12.019. - DOI - PubMed
    1. Mulder CH, Kalaykova SI, Gortzak RA. Coronoid process hyperplasia: a systematic review of the literature from 1995. Int J Oral Maxillofac Surg. 2012;41:1483–9. doi: 10.1016/j.ijom.2012.03.029. https://doi.org/10.1016/j.ijom.2012.03.029. - DOI - PubMed