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Review
. 2023 May;201(5):2222-2239.
doi: 10.1007/s12011-022-03346-9. Epub 2022 Jun 30.

Boron-Containing Compounds for Prevention, Diagnosis, and Treatment of Human Metabolic Disorders

Córdova-Chávez Ri #  1 , Carrasco-Ruiz Mf #  1 , Rodríguez-Vera D  1 , Pérez-Capistran T  1 , Tamay-Cach F  2 , Scorei Ir  3 , Abad-García A  4 , Soriano-Ursúa Ma  5
Affiliations
Review

Boron-Containing Compounds for Prevention, Diagnosis, and Treatment of Human Metabolic Disorders

Córdova-Chávez Ri et al. Biol Trace Elem Res. 2023 May.

Abstract

The application of natural and synthetic boron-containing compounds (BCC) in biomedical field is expanding. BCC have effects in the metabolism of living organisms. Some boron-enriched supplements are marketed as they exert effects in the bone and skeletal muscle; but also, BCC are being reported as acting on the enzymes and transporters of membrane suggesting they could modify the carbohydrate metabolism linked to some pathologies of high global burden, as an example is diabetes mellitus. Also, some recent findings are showing effects of BCC on lipid metabolism. In this review, information regarding the effects and interaction of these compounds was compiled, as well as the potential application for treating human metabolic disorders is suggested.

Keywords: Bodipy; Boron; Boronic acids; Diabetes; Metabolic diseases; Metabolic profile.

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