Histochemical Staining of Vasculogenic Mimicry
- PMID: 35771423
- DOI: 10.1007/978-1-0716-2403-6_11
Histochemical Staining of Vasculogenic Mimicry
Abstract
Vasculogenic mimicry (VM) describes a new tumor microvascular paradigm of non-endothelial cells, where aggressive cancer cells independent of angiogenesis acquire the ability to fluid-conducting vessels. VM shows worse 5-year overall survival in cancer that suggesting that VM could be a promising surgical and effective adjuvant therapy strategy in prognostics of metastatic cancer patients. The current chapter is a comprehensive review on "Main Staining Methods and Protocols in Vasculogenic Mimicry." Here, we provide most up-to-date and detailed information upon microscopy and histology protocols for the identification and understanding of VM process in both in vitro and in vivo.
Keywords: Diagnosis; Endothelial markers; Immunohistochemistry; Malignancy; Paraffin-embedded tissue specimens; Periodic acid; Schiff; Vasculogenic mimicry.
© 2022. Springer Science+Business Media, LLC, part of Springer Nature.
Similar articles
-
Clinical significance of vasculogenic mimicry in human gliomas.J Neurooncol. 2011 Nov;105(2):173-9. doi: 10.1007/s11060-011-0578-5. Epub 2011 Apr 30. J Neurooncol. 2011. PMID: 21533525 Free PMC article.
-
Identification of Vasculogenic Mimicry in Histological Samples.Methods Mol Biol. 2022;2514:121-128. doi: 10.1007/978-1-0716-2403-6_12. Methods Mol Biol. 2022. PMID: 35771424
-
Vasculogenic Mimicry-An Overview.Methods Mol Biol. 2022;2514:3-13. doi: 10.1007/978-1-0716-2403-6_1. Methods Mol Biol. 2022. PMID: 35771413
-
Mechanisms of vasculogenic mimicry in hypoxic tumor microenvironments.Mol Cancer. 2021 Jan 4;20(1):7. doi: 10.1186/s12943-020-01288-1. Mol Cancer. 2021. PMID: 33397409 Free PMC article. Review.
-
Regulatory mechanisms and therapeutic targeting of vasculogenic mimicry in hepatocellular carcinoma.Pharmacol Res. 2021 Apr;166:105507. doi: 10.1016/j.phrs.2021.105507. Epub 2021 Feb 18. Pharmacol Res. 2021. PMID: 33610718 Review.
Cited by
-
Mechanisms of angiogenesis in tumour.Front Oncol. 2024 Mar 25;14:1359069. doi: 10.3389/fonc.2024.1359069. eCollection 2024. Front Oncol. 2024. PMID: 38590656 Free PMC article. Review.
-
Comparative mRNA/micro-RNA co-expression network drives melanomagenesis by promoting epithelial-mesenchymal transition and vasculogenic mimicry signaling.Transl Oncol. 2021 Dec;14(12):101237. doi: 10.1016/j.tranon.2021.101237. Epub 2021 Oct 6. Transl Oncol. 2021. PMID: 34626953 Free PMC article.
-
The role of TOP2A in immunotherapy and vasculogenic mimicry in non-small cell lung cancer and its potential mechanism.Sci Rep. 2023 Jul 5;13(1):10906. doi: 10.1038/s41598-023-38117-6. Sci Rep. 2023. PMID: 37407689 Free PMC article.
References
-
- Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646–674. https://doi.org/10.1016/j.cell.2011.02.013 - DOI - PubMed
-
- Qiao L, Liang N, Zhang J (2015) Advanced research on vasculogenic mimicry in cancer. J Cell Mol Med 19:315–326. https://doi.org/10.1016/j.cell.2011.02.013 - DOI - PubMed - PMC
-
- Folberg R, Hendrix MJ, Maniotis AJ (2000) Vasculogenic mimicry and tumor angiogenesis. Am J Pathol 156:361–381. https://doi.org/10.1016/S0002-9440(10)64739-6 - DOI - PubMed - PMC
-
- Feng Y, Wang B, Liang G et al (2015) Relationship between vasculogenic mimicry and clinic pathological features in laryngeal carcinoma. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 29:2071–2075 - PubMed
-
- Shirakawa K, Kobayashi H, Heike Y et al (2002) Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft. Cancer Res 62:560–566 - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
