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Comment

. 2022 Jul;377(6601):31-32.

doi: 10.1126/science.adc9969. Epub 2022 Jun 30.

Elucidating the causes of neurodegeneration

Gregory A Petsko¹, Scott A Small²

Affiliations

Affiliations

¹ Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham & Women's Hospital and Harvard Medical School, Boson, MA, USA.
² Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.

PMID: 35771902
DOI: 10.1126/science.adc9969

Comment

Elucidating the causes of neurodegeneration

Gregory A Petsko et al. Science. 2022 Jul.

. 2022 Jul;377(6601):31-32.

doi: 10.1126/science.adc9969. Epub 2022 Jun 30.

Authors

Gregory A Petsko¹, Scott A Small²

Affiliations

¹ Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham & Women's Hospital and Harvard Medical School, Boson, MA, USA.
² Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.

PMID: 35771902
DOI: 10.1126/science.adc9969

Abstract

Investigating phase separation in neurodegeneration highlights evidence needed for causation.

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Comment on

Mutations linked to neurological disease enhance self-association of low-complexity protein sequences.
Zhou X, Sumrow L, Tashiro K, Sutherland L, Liu D, Qin T, Kato M, Liszczak G, McKnight SL. Zhou X, et al. Science. 2022 Jul;377(6601):eabn5582. doi: 10.1126/science.abn5582. Epub 2022 Jul 1. Science. 2022. PMID: 35771920 Free PMC article.

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