Knowledge from the Noise: A Regression Discontinuity Design to Inform Optimal Transfusion Thresholds for Critically Ill Patients
- PMID: 35772100
- PMCID: PMC9278634
- DOI: 10.1513/AnnalsATS.202203-259ED
Knowledge from the Noise: A Regression Discontinuity Design to Inform Optimal Transfusion Thresholds for Critically Ill Patients
Figures


Comment on
-
Red Blood Cell Transfusion at a Hemoglobin Threshold of 7 g/dl in Critically Ill Patients: A Regression Discontinuity Study.Ann Am Thorac Soc. 2022 Jul;19(7):1177-1184. doi: 10.1513/AnnalsATS.202109-1078OC. Ann Am Thorac Soc. 2022. PMID: 35119978 Free PMC article.
References
-
- Hébert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med . 1999;340:409–417. - PubMed
-
- Vincent JL, Sakr Y, Sprung C, Harboe S, Damas P, Sepsis Occurrence in Acutely Ill Patients (SOAP) Investigators Are blood transfusions associated with greater mortality rates? Results of the Sepsis Occurrence in Acutely Ill Patients study. Anesthesiology . 2008;108:31–39. - PubMed
-
- Toy P, Popovsky MA, Abraham E, Ambruso DR, Holness LG, Kopko PM, et al. National Heart, Lung and Blood Institute Working Group on TRALI Transfusion-related acute lung injury: definition and review. Crit Care Med . 2005;33:721–726. - PubMed
-
- Zallen G, Offner PJ, Moore EE, Blackwell J, Ciesla DJ, Gabriel J, et al. Age of transfused blood is an independent risk factor for postinjury multiple organ failure. Am J Surg . 1999;178:570–572. - PubMed
-
- Vincent JL, Baron JF, Reinhart K, Gattinoni L, Thijs L, Webb A, et al. ABC (Anemia and Blood Transfusion in Critical Care) Investigators Anemia and blood transfusion in critically ill patients. JAMA . 2002;288:1499–1507. - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources