Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Apr 25;14(2):33670.
doi: 10.52965/001c.33670. eCollection 2022.

Debridement and implant retention in acute hematogenous periprosthetic joint infection after knee arthroplasty: a systematic review

Affiliations
Review

Debridement and implant retention in acute hematogenous periprosthetic joint infection after knee arthroplasty: a systematic review

Giovanni Balato et al. Orthop Rev (Pavia). .

Abstract

Debridement, antibiotic, and implant retention (DAIR) can be used as a first surgical procedure for acute infections in patients who have well-fixed components. However, its use in hematogenous or late acute infections is still debated. This systematic review of literature aims to clarify the effectiveness of DAIR procedure in the treatment of hematogenous periprosthetic knee infections. DAIR is an effective way to treat acute hematogenous PJIs of the knee and reaches its best efficacy when performed within one week from the onset of symptoms, modular components are exchanged, and a pathogen-oriented antibiotic therapy can be set. It is safe, economic, and effective technique, but has to be performed in a very narrow temporal window.

Keywords: Acute hematogenous infection; Infection; Knee Joint; PJI.

PubMed Disclaimer

Conflict of interest statement

No author is involved in a conflict of interest. No author has received any funding.

Figures

Figure 1.
Figure 1.

Similar articles

Cited by

References

    1. 1. Triantafyllopoulos GK, Poultsides LA, Zhang W, Sculco PK, Ma Y, Sculco TP. Periprosthetic knee infections treated with irrigation and debridement: outcomes and preoperative predictive factors. J Arthroplasty. 2015;30(4):649-657. doi:10.1016/j.arth.2014.10.026 - PubMed
    1. 2. Zhang C, Yan C, Chan P, Chiu K, Ng F. Polyethylene Insert Exchange Is Crucial in Debridement for Acute Periprosthetic Infections following Total Knee Arthroplasty. J Knee Surg. 2017;30(01):36-41. doi:10.1055/s-0036-1579667 - PubMed
    1. 3. Balato G, Di Matteo V, Di Franco C, et al. Prevention and treatment of peri-prosthetic joint infection using surgical wound irrigation. J Biol Regul Homeost Agents. 2020;34(5):17-23. https://pubmed.ncbi.nlm.nih.gov/33739000/ - PubMed
    1. 4. Ascione T, Balato G, Mariconda M, Rotondo R, Baldini A, Pagliano P. Continuous Antibiotic Therapy Can Reduce Recurrence of Prosthetic Joint Infection in Patients Undergoing 2-Stage Exchange. J Arthroplasty. 2019;34(4):704-709. doi:10.1016/j.arth.2018.12.017 - PubMed
    1. 5. Ascione T, Pagliano P, Mariconda M, et al. Factors related to outcome of early and delayed prosthetic joint infections. J Infect. 2015;70(1):30-36. doi:10.1016/j.jinf.2014.07.008 - PubMed