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Case Reports
. 2022 Nov;22(11):2694-2696.
doi: 10.1111/ajt.17134. Epub 2022 Jul 9.

Successful liver transplantation in patients with active SARS-CoV-2 infection

Charles A Mouch  1 , Sophoclis P Alexopoulos  1 , Richard W LaRue  2 , Hannah P Kim  3
Affiliations
Case Reports

Successful liver transplantation in patients with active SARS-CoV-2 infection

Charles A Mouch et al. Am J Transplant. 2022 Nov.

Abstract

The Coronavirus Disease 2019 (COVID-19) pandemic has substantially impacted solid organ transplantation, including temporary inactivation of waitlist candidates with COVID-19 infection. We report two cases of liver transplantation (LT) in individuals with asymptomatic COVID-19 infection. The first patient is a 68-year-old female with decompensated cirrhosis complicated by worsening frailty and sarcopenia. The second patient is a 22-year-old female with acute liver failure likely secondary to drug/toxin exposure. Both patients were treated with COVID-19-directed therapies and neither patient developed symptomatic disease. These cases demonstrate that LT can be safely performed in select patients with asymptomatic COVID-19 infection at the time of transplant.

Keywords: clinical research/practice; infection and infectious agents - viral: SARS-CoV-2/COVID-19; liver transplantation/hepatology; patient safety.

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