Mapping the malignant transformation from polyps to CRC

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Katrina Ray. Nat Rev Gastroenterol Hepatol. 2022 Aug.

. 2022 Aug;19(8):488.

doi: 10.1038/s41575-022-00660-4.

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Single-cell analyses define a continuum of cell state and composition changes in the malignant transformation of polyps to colorectal cancer.
Becker WR, Nevins SA, Chen DC, Chiu R, Horning AM, Guha TK, Laquindanum R, Mills M, Chaib H, Ladabaum U, Longacre T, Shen J, Esplin ED, Kundaje A, Ford JM, Curtis C, Snyder MP, Greenleaf WJ. Becker WR, et al. Nat Genet. 2022 Jul;54(7):985-995. doi: 10.1038/s41588-022-01088-x. Epub 2022 Jun 20. Nat Genet. 2022. PMID: 35726067 Free PMC article.

1. Becker, W. R. et al. Single-cell analyses define a continuum of cell state and composition changes in the malignant transformation of polyps to colorectal cancer. Nat. Genet. https://doi.org/10.1038/s41588-022-01088-x (2022) - DOI - PubMed - PMC