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Review
. 2022 Sep 1;35(5):305-310.
doi: 10.1097/YCO.0000000000000806. Epub 2022 Jul 5.

The physical and mental health consequences of social isolation and loneliness in the context of COVID-19

Affiliations
Review

The physical and mental health consequences of social isolation and loneliness in the context of COVID-19

Nagesh Pai et al. Curr Opin Psychiatry. .

Abstract

Purpose of review: Social isolation and loneliness are known contributors to all-cause mortality as well as a range of physical and mental health conditions. Therefore, this article reviews current literature pertaining to the effects of social isolation and loneliness on physical and mental health during the current COVID-19 pandemic.

Recent findings: Social isolation and loneliness contribute to a myriad of physical and mental health conditions. Specifically social isolation and loneliness contribute to the development of cardiovascular disease, diabetes mellitus, and cancer. However, most research indicated that poor lifestyle factors explained most of the association. Social isolation and loneliness are also associated with cognitive problems including dementia, immune system problems, and mental health conditions. Further social isolation and loneliness also spur behavioral issues that significantly affect physical and mental health.

Summary: Evidence suggests that social isolation and loneliness have significant consequences on the physical and mental health of the individual and that the move toward ending all protections against COVID-19 has significant implications for the vulnerable. Further the similarities between the effects of social isolation and loneliness are compared to some of the conditions evident in long-COVID.

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References

    1. Fakoya OA, McCorry N, Donnelly M. Loneliness and social isolation interventions for older adults: a scoping review of reviews. BMC Public Health 2020; 20:129.
    1. Banerjee D, Rai M. Social isolation in COVID-19: the impact of loneliness. Int J Soc Psychiatr 2020; 66:525–527.
    1. Escalante E, Mason DJ. Social isolation and loneliness: imperatives for healthcare in a post-COVID world. JAMA 2021; 325:520.
    1. Pai N, Vella SC. COVID-19 and loneliness: a rapid systematic review. Aust N Z J Psychiatry 2021; 53:1144–1156.
    1. Worldometer.(2022). Worldometer coronoavirus. https://www.worldometers.info/coronavirus /: accessed on 4/03/22.