ONS Guidelines™ to Support Patient Adherence to Oral Anticancer Medications
- PMID: 35788731
- PMCID: PMC9303042
- DOI: 10.1188/22.ONF.279-295
ONS Guidelines™ to Support Patient Adherence to Oral Anticancer Medications
Abstract
Purpose: This evidence-based guideline intends to support patients, clinicians, and others regarding interventions and processes to support patient adherence to oral anticancer medications (OAMs).
Methodologic approach: A panel of healthcare professionals and patient representatives developed a clinical practice guideline to support patients taking OAMs. GRADE (Grading of Recommendations Assessment, Development, and Evaluation) methodology and criteria for trustworthy guidelines were followed. Risk of bias was assessed using the Cochrane Risk of Bias 2 tool. A quantitative or narrative synthesis of the evidence was completed. Certainty of the evidence was assessed using GRADE.
Findings: The panel agreed on recommendations and suggested an adherence risk assessment, education addressing adherence, ongoing assessment, proactive follow-up, coaching, and motivational interviewing in addition to usual care. The panel suggested the implementation of a structured OAM program.
Implications for nursing: As cancer treatment shifts from clinic to home settings, interventions and programs to support patients on OAMs are needed.
Keywords: medication adherence; nursing; oncology care; oral anticancer medication; scoping review.
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References
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- Alonso-Coello P, Oxman AD, Moberg J, Brignardello-Petersen R, Akl EA, Davoli M,… Schünemann HJ (2016). GRADE Evidence to Decision (EtD) frameworks: A systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines. BMJ, 353, i2089. 10.1136/bmj.i2089 - DOI - PubMed
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- Arthurs G, Simpson J, Brown A, Kyaw O, Shyrier S, & Concert CM (2015). The effectiveness of therapeutic patient education on adherence to oral anti-cancer medicines in adult cancer patients in ambulatory care settings: A systematic review. JBI Database of Systematic Reviews and Implementation Reports, 13(5), 244–292. 10.11124/jbisrir-2015-2057 - DOI - PubMed
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