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Review
. 2022 Jul 6;6(1):28.
doi: 10.1186/s41747-022-00280-2.

Preoperative localisation of nonpalpable breast lesions using magnetic markers in a tertiary cancer centre

Antonella Petrillo  1 , Raimondo Di Giacomo  2 , Emanuela Esposito  2 , Paolo Vallone  3 , Sergio Venanzio Setola  3 , Mauro Mattace Raso  3 , Vincenza Granata  3 , Maria Luisa Barretta  3 , Claudio Siani  2 , Chiara Rinaldo  4 , Ivana Donzelli  2 , Ugo Marone  2 , Maria Teresa Melucci  2 , Alfredo Fucito  2 , Ruggero Saponara  2 , Maurizio Di Bonito  5 , Roberta Fusco  6 , Massimo Rinaldo  2 , Franca Avino  2
Affiliations
Review

Preoperative localisation of nonpalpable breast lesions using magnetic markers in a tertiary cancer centre

Antonella Petrillo et al. Eur Radiol Exp. .

Abstract

Background: We retrospectively evaluated safety and performance of magnetic seed localisation of nonpalpable breast lesions.

Methods: We reviewed records of patients with nonpalpable breast lesions preoperative localised by placing magnetic Magseed® marker between February 2019 and December 2020. During surgery, Sentimag® magnetic probe was used to localise the marker and guide surgery. Safety, lesion identification and excision with tumour with free margins and re-excision rate were assessed.

Results: A total of 77 Magseed® devices were placed into the breasts of 73 patients, 44 under ultrasound and 33 under stereotactic guidance (4 bilateral). All devices were retrieved as were the target lesions. Magnetic marker placement was successful in all cases without any adverse event. Intraoperative identification and excision of the localised lesion were successful in 77 of 77 of cases (100%). In three cases (all of them calcifications with the seed placed under stereotactic guidance), the seed did not reach the exact target position of the biopsy clip; thus, larger excision was needed, with localisation failure attributed to incorrect clip insertion (n = 1) or to clip dislocation (n = 2). Migration of the marker was negligible in all patients. Complete excision after the initial procedure with at least 1-mm disease-free margins was obtained in 74 out of 77 (96.1%) lesions. The re-excision rate was 3 out of 77 (4%).

Conclusions: Magnetic marker localisation for nonpalpable breast lesions was safe, reliable, and effective in terms of lesion identification, excision with tumour-free margins and re-excision rate.

Keywords: Breast neoplasms; Magnetics; Margins of excision; Preoperative (procedure); Reoperation.

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Conflict of interest statement

Roberta Fusco is an employee of Igea SpA. The remaining authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Examples of specimen radiographs showing the identification target in the centre of the lesion
Fig. 2
Fig. 2
Small periareolar incision performed with preoperative lesion localisation using Magseed® and Sentimag® (a). Monitor showing magnetic field (b). Specimen containing Magseed® (c)
See this image and copyright information in PMC

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